000 01868cam a22003974a 4500
001 15928530
003 BD-DhUL
005 20150912115821.0
008 090929s2010 njua b 001 0 eng
010 _a 2009040188
015 _2bnb
_aGBA9A0428
016 7 _a101516110
_2DNLM
016 7 _a015392203
_2Uk
020 _a9780470257616 (cloth)
020 _a047025761X (cloth)
035 _a(OCoLC)ocn435422355
040 _aDNLM/DLC
_cDLC
_dYDX
_dNLM
_dBTCTA
_dYDXCP
_dUKM
_dDLC
_dDLC
042 _apcc
050 0 0 _aRM301.25
_b.L433 2010
060 0 0 _a2010 D-768
060 1 0 _aQV 744
_bL4345 2010
082 0 0 _a615.19
_222
_bRAL
245 0 0 _aLead generation approaches in drug discovery /
_c[edited by] Zoran Rankovic, Richard Morphy.
260 _aHoboken, N.J. :
_bJohn Wiley,
_cc2010.
300 _axi, 295 p. :
_bill. ;
_c25 cm.
365 _aUS$
_b106.15
504 _aIncludes bibliographical references and index.
505 0 _aLead discovery : the process / William F. Michne -- High throughput screening approach to lead discovery / Zoran Rankovic, Craig Jamieson, and Richard Morphy -- In silico screening / Dagmar Stumpfe, Hanna Geppert, and Jürgen Bajorath -- Fragment-based lead discovery / Jeffrey S. Albert -- Design of multitarget ligands / Richard Morphy and Zoran Rankovic -- De novo drug design / Gisbert Schneider, Markus Hartenfeller, Ewgenij Proschak -- Role of natural products in drug discovery / Hugo Lachance, Stefan Wetzel, and Herbert Waldmann -- Early screening for ADMET properties / Dennis A. Smith -- Role of chemistry in lead discovery / Roland E. Dolle and Karin Worm.
650 0 _aDrug development.
650 0 _aDrugs
_xDesign.
650 0 _aHigh throughput screening (Drug development)
650 1 2 _aDrug Discovery
_xmethods.
700 1 _aRankovic, Zoran.
700 1 _aMorphy, Richard.
942 _2ddc
_cBK
999 _c41576
_d41576