| 000 | 02346cam a22004338a 4500 | ||
|---|---|---|---|
| 001 | 16780199 | ||
| 003 | BD-DhUL | ||
| 005 | 20150120190900.0 | ||
| 008 | 110512s2012 nyu b 001 0 eng | ||
| 010 | _a 2011020446 | ||
| 020 | _a9780071603935 (hardcover : alk. paper) | ||
| 020 | _a007160393X (hardcover : alk. paper) | ||
| 035 | _a(DNLM)101560548 | ||
| 040 |
_aBD-DhUL _cBD-DhUL |
||
| 042 | _apcc | ||
| 050 | 0 | 0 |
_aRM301.4 _b.S52 2012 |
| 060 | 1 | 0 | _aQV 38 |
| 082 | 0 | 0 |
_a615.7 _bSHA |
| 100 | 1 | _aShargel, Leon, | |
| 245 | 1 | 0 |
_aApplied biopharmaceutics & pharmacokinetics / _cLeon Shargel, Andrew B.C. Yu, Susanna Wu-Pong. |
| 246 | 1 | _aApplied biopharmaceutics and pharmacokinetics | |
| 250 | _a6th ed. | ||
| 260 |
_aNew York : _bMcGraw-Hill, _c2012. |
||
| 263 | _a1212 | ||
| 300 |
_axi, 811 p. : _c22 cm. _bill. ; |
||
| 365 |
_a$ _b75.00 |
||
| 504 | _aIncludes bibliographical references and index. | ||
| 505 | 0 | _aIntroduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- One-compartment open model: intravenous bolus administration -- Multicompartmental models : intravenous bolus administration -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Drug elimination and hepatic clearance -- Pharmacogenetics -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design and in vitro drug product performance -- Drug product performance, in vivo : bioavailability and bioequivalence -- Impact of drug product quality and biopharmaceutics on clinical efficacy -- Modified-release drug products -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetics and pharmacodynamics -- Application of pharmacokinetics to clinical situations -- Dosage adjustment in renal and hepatic disease. | |
| 650 | 0 | _aBiopharmaceutics. | |
| 650 | 0 | _aPharmacokinetics. | |
| 650 | 1 | 2 | _aBiopharmaceutics. |
| 650 | 2 | 2 | _aModels, Chemical. |
| 650 | 2 | 2 | _aPharmacokinetics. |
| 700 | 1 |
_aYu, Andrew B. C., _d1945- |
|
| 700 | 1 | _aWu-Pong, Susanna. | |
| 906 |
_a7 _bcbc _corignew _d1 _eecip _f20 _gy-gencatlg |
||
| 942 |
_2ddc _cBK |
||
| 955 | _bxh11 2011-06-17 | ||
| 999 |
_c34146 _d34146 |
||