000 05928cam a2200721Ia 4500
001 ocn882769713
003 OCoLC
005 20190328114808.0
006 m o d
007 cr cnu---unuuu
008 140705s2014 cau o 001 0 eng d
040 _aEBLCP
_beng
_epn
_cEBLCP
_dN$T
_dOPELS
_dIDEBK
_dYDXCP
_dUIU
_dSTF
_dUKMGB
_dNEH
_dCDX
_dOCLCQ
_dOCLCF
_dOCLCQ
_dUUM
_dU3W
_dCHVBK
_dOTZ
_dOCLCQ
016 7 _a016831014
_2Uk
019 _a882610681
020 _a9780124171343
_q(electronic bk.)
020 _a0124171346
_q(electronic bk.)
020 _a1306902541
_q(ebk)
020 _a9781306902540
_q(ebk)
020 _z9780124171145
020 _z0124171141
035 _a(OCoLC)882769713
_z(OCoLC)882610681
050 4 _aRC341 .P393 2014
060 4 _aWM 140
072 7 _aHEA
_x039000
_2bisacsh
072 7 _aMED
_x014000
_2bisacsh
072 7 _aMED
_x022000
_2bisacsh
072 7 _aMED
_x112000
_2bisacsh
072 7 _aMED
_x045000
_2bisacsh
082 0 4 _a616.8
_222
245 0 0 _aEpigenetics in psychiatry /
_h[electronic resource]
_cedited by Jacob Peedicayil, Dennis R. Grayson, Dimitrios Avramopoulos.
260 _aSan Diego, CA :
_bAcademic Press,
_c�2014.
300 _a1 online resource (664 pages)
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
500 _aIncludes index.
520 _aEpigenetics in Psychiatry covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this potentially very important and useful area of psychiatry. The elucidation of basic principles o.
588 0 _aPrint version record.
505 0 _aFront Cover; Epigenetics in Psychiatry; Copyright Page; Contents; Preface; About the Editors; List of Contributors; 1 General Aspects of Epigenetics in Psychiatry; 1 Introduction to Epigenetics in Psychiatry; Introduction; Genetics of psychiatric disorders; Schizophrenia; Autism spectrum disorder; Bipolar disorder; Major depressive disorder; Attention deficit hyperactivity disorder; Genotype versus phenotype; Missing heritability; Epigenetics in psychiatric disorders; Nutrition; Prenatal infection; Stress; Epigenetic versus genetic approaches to psychiatric disorders.
505 8 _aMoving epigenetics forwardConclusion; References; Glossary; 2 Outline of Epigenetics; Introduction; Molecular mechanisms of epigenetics; DNA methylation; DNA methylation, development, and disease; Chromatin remodeling and histone modifications; Histone acetylation; Histone methylation; Other histone modifications; Non-Coding RNA; microRNA; Correlation of epigenetics with genetics, transcriptomics, and proteomics; Clinical and medical implication of epigenetics; Conclusion; Acknowledgments; References; Glossary; 3 A Brief History of Epigenetics in Psychiatry; Introduction.
505 8 _aErikson's epigenetic principleSchizophrenia: the epigenetic puzzle; Later theoretical developments; Experimental (laboratory) studies on epigenetics in psychiatry; The social environment and epigenetics in psychiatry; Conclusions; References; Glossary; 4 Roles of Epigenetics in the Neural Stem Cell and Neuron; Outline of neural cell production during cortical development; Epigenetic regulation of exit from cell proliferation cycle toward postmitotic neurons during early cortical development.
505 8 _aEpigenetic regulation underlying properties of multipotent neural stem cells and their differentiation into upper layer cor ... Epigenetic regulation of postnatal oligodendrocyte differentiation and adult neurogenesis; Combination of trans-acting epigenetic modifiers involved in epigenome formation; Importance of focusing on epigenetics in neuronal functions; Impact of epigenetic regulation on synaptic plasticity, learning, and memory; Plasticity of epigenetic profile in neurons in response to extrinsic stimuli; The robust identity of neurons defined by the epigenetic status.
505 8 _aConcluding remarksAcknowledgments; References; Glossary; 5 Role of Epigenetics in the Brain; Introduction; Role of epigenetics in evolution; Role of epigenetics in brain development; Brain development; Epigenetics in early brain development; Epigenetics in adult neurogenesis and later brain maturation; Epigenetics and extrinsic factors regulating brain development; Role of epigenetic mechanisms in brain function; Epigenetics and memory; Epigenetics and stress; Epigenetics and cognitive dysfunction; Concluding remarks; Acknowledgments; References; Glossary.
650 0 _aMental illness
_xEtiology.
650 0 _aMental illness
_xPathophysiology.
650 0 _aNeuropsychiatry.
650 7 _aHEALTH & FITNESS
_xDiseases
_xGeneral.
_2bisacsh
650 7 _aMEDICAL
_xClinical Medicine.
_2bisacsh
650 7 _aMEDICAL
_xDiseases.
_2bisacsh
650 7 _aMEDICAL
_xEvidence-Based Medicine.
_2bisacsh
650 7 _aMEDICAL
_xInternal Medicine.
_2bisacsh
650 7 _aMental illness
_xEtiology.
_2fast
_0(OCoLC)fst01016573
650 7 _aMental illness
_xPathophysiology.
_2fast
_0(OCoLC)fst01016584
650 7 _aNeuropsychiatry.
_2fast
_0(OCoLC)fst01036481
650 1 2 _aMental Disorders
_xetiology.
650 2 2 _aNeuropsychiatry.
655 4 _aElectronic books.
700 1 _aPeedicayil, Jacob.
700 1 _aGrayson, Dennis R.
700 1 _aAvramopoulos, Dimitri.
776 0 8 _iPrint version:
_aPeedicayil, Jacob.
_tEpigenetics in Psychiatry.
_dBurlington : Elsevier Science, 2014
_z9780124171145
856 4 0 _3ScienceDirect
_uhttp://www.sciencedirect.com/science/book/9780124171145
999 _c246926
_d246926