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001 ocn846849851
003 OCoLC
005 20171106103140.0
006 m o d
007 cr cn|||||||||
008 130605t20132013gw a ob 001 0 eng d
016 7 _a016329591
_2Uk
020 _a9783527654628
_q(electronic bk.)
020 _a3527654623
_q(electronic bk.)
020 _a9783527654659
_q(ePDF)
020 _a3527654658
_q(ePDF)
020 _a9783527654642
_q(ePub)
020 _a352765464X
_q(ePub)
020 _a9783527654635
_q(mobi)
020 _a3527654631
_q(mobi)
020 _a9783527654628
_q(oBook)
020 _a1299738109
020 _a9781299738102
020 _z9783527329762
_q(Print)
020 _z3527329765
_q(Print)
029 1 _aAU@
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029 1 _aDEBBG
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029 1 _aDEBBG
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029 1 _aDEBBG
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029 1 _aGBVCP
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029 1 _aNZ1
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035 _a(OCoLC)846849851
_z(OCoLC)855905996
_z(OCoLC)895736998
_z(OCoLC)961669377
_z(OCoLC)962586747
037 _a505061
_bMIL
040 _aDG1
_beng
_epn
_cDG1
_dCUS
_dOCLCO
_dUKMGB
_dYDXCP
_dN$T
_dNOC
_dE7B
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_dOCLCQ
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049 _aMAIN
050 4 _aQD262
_b.S54 2013
072 7 _aSCI
_x013040
_2bisacsh
082 0 4 _a547/.2
_223
100 1 _aSierra, Miguel A.
_q(Miguel Angel),
_eauthor.
245 1 0 _aMore dead ends and detours : en route to successful total synthesis /
_cMiguel A. Sierra, María C. de la Torre, and Fernando P. Cossío.
_h[electronic resource]
250 _aFirst edition.
264 1 _aWeinheim, Germany :
_bWiley-VCH Verlag GmbH & Co. KGaA,
_c2013.
264 4 _c©2013
300 _a1 online resource (xxi, 266 pages) :
_billustrations
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
500 _aEdition statement from first page of chapter PDFs.
504 _aIncludes bibliographical references and index.
505 0 _aThe Inertia of Conventional Functional Groups -- The Diels-Alder Reaction -- The Aldol Condensation -- Cyclizations: Concerted, Radical, or Polar? -- Macrocycles: From Reluctant Ring Closure to Reluctant Ring Opening -- Stereochemistry, Controlled or Uncontrolled? -- Transition Metal-Mediated Transformations vs "Conventional" Reactions -- When Metathesis Fails -- Oxidations in C-C Bond Building -- The Failure of Epoxide Ring Opening and the Limits of Cascade Reactions.
520 3 _aSuccess comes in many forms and in synthesis it can be a failure that results in their ultimate successful solutions. This long-awaited sequel to "Dead Ends and Detours" retains the proven concept while featuring over 20 new case studies of failed strategies and their (successful) solutions in natural product total synthesis. Additionally, computational models are used to discuss the problem in much more detail and to provide readers with additional information not found in the primary literature. The topics range from classic synthetic reactions (e.g. Diels Alder reaction), metal-mediated coupling reactions, metathesis, and asymmetric catalysis to the importance of protecting and activating groups. This book will benefit not only graduate students in organic chemistry but also advanced researchers as they gain knowledge derived from the step-by-step analysis of mistakes made in the past and, thus be able to improve their own chemical reaction planning. With its coverage of the most commonly applied reaction types, the book perfectly complements its predecessor, which focuses on general aspects, such as reactivity and selectivity.
588 0 _aOnline resource; title from PDF title page (viewed May 7, 2014).
650 0 _aOrganic compounds
_xSynthesis.
650 7 _aSCIENCE
_xChemistry
_xOrganic.
_2bisacsh
650 7 _aOrganic compounds
_xSynthesis.
_2fast
_0(OCoLC)fst01047668
655 4 _aElectronic books.
655 7 _aElectronic books.
_2local
700 1 _aTorre, María C. de la,
_eauthor.
700 1 _aCossío, Fernando P.,
_eauthor.
776 0 8 _iPrint version:
_aSierra, Miguel A.
_tMore dead ends and detours.
_dWeinheim : Wiley-Vch, 2013
_z3527329765
_w(OCoLC)823380609
856 4 0 _uhttp://onlinelibrary.wiley.com/book/10.1002/9783527654628
_zWiley Online Library
942 _2ddc
_cBK
999 _c206802
_d206802