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020 _a9781849731294
020 _a1849731292 (Trade Cloth)
_cUSD 243.00 Retail Price (Ingram Publisher Services)
024 3 _a9781849731294
035 _a(WaSeSS)ssj0000578409
037 _b00154291
040 _aBIP US
_dWaSeSS
_dBD-DhUL
_cBD-DhUL
050 4 _aQD341.A6
082 0 0 _a547.27
_222
_bCHE
100 1 _aShi, Min
_eAuthor
210 1 0 _aThe Chemistry of the Morita-Baylis-Hillman Reaction
245 1 4 _aThe Chemistry of the Morita-Baylis-Hillman Reaction
260 _aCambridge :
_bRoyal Society of Chemistry, The
_cApril 2011
_aLaVergne :
_bIngram Publisher Services [Distributor]
490 _aRSC Catalysis Ser.
520 8 _aAnnotation
_bCarbon-carbon bond formations and functional group transformations are the most fundamental reactions for the construction of molecular frameworks and are at the forefront of organic chemistry research. The Morita-Baylis-Hillman (MBH) type reactions possess the two most important requirements - atom economy and generation of multi-functional groups. The last decade has seen exponential growth of the MBH reaction and its applications. In fact, it is already one of the most powerful carbon-carbon bond-forming methods widely used in organic synthesis. Since the 1990s, more and more research groups have initiated work on different aspects of the MBH reaction. These have focused on the scope of the substrates, novel catalysts (especially chiral catalysts), reaction mechanisms, and synthetic applications. Consequently, there is now a need for a reference detailing the chemistry of this important reaction. This unique book summarizes the MBH reaction, aza-MBH reaction and asymmetric MBH/aza-MBH reaction including the latest research and mechanistic investigations. It provides a complete overview of MBH-type reactions aimed at synthetic organic chemists of all levels within academia and industry. The chapters cover the; origin and growth of the Morita-Baylis-Hillman reaction; reactant classes and reaction conditions; catalytic mechanisms; achiral and chiral catalytic systems; transformations of functional groups; use of Morita-Baylis-Hillman adducts and derivatives as starting materials to construct compounds with carbocyclic or heterocyclic frameworks, and the applications of the MBH reaction in synthesizing natural products.
700 1 _aWang, Feijun
_eAuthor
700 1 _aZhao, Mei-Xin
_eAuthor
700 1 _aWei, Yin
_eAuthor
700 1 _aSpivey, J. J.
_eContribution by
_4oth
942 _2ddc
_cBK
999 _c16148
_d16148