01453cam a2200313 a 450000100090000000300080000900500170001700800410003401000170007502000260009202000250011803500200014304000320016304200080019505000240020306000120022708200200023924500890025926000700034830000390041836500150045750400510047250504850052365000320100865000310104065000270107165000200109870000210111817443364BD-DhUL20151014093638.0120824s2013 enka b 001 0 eng  a 2012034772 a9780470684443 (cloth) a9780470684436 (pbk.) a(DNLM)101591061 aDNLM/DLCcDLCdDLCdBD-DhUL apcc00aRM301.65b.M65 201310aQV 38.500a615.19223bMOL00aMolecular pharmacology :bfrom DNA to drug discovery /cJohn Dickenson ... [et al.]. aChichester, West Sussex ;aHoboken, NJ :bWiley-Blackwell,c2013. axiv, 409 p. :bcol. ill. ;c26 cm. aUS$b95.95 aIncludes bibliographical references and index.0 aIntroduction to drug targets and molecular pharmacology -- Molecular cloning of drug targets -- G protein-coupled receptors -- Ion channels -- Transporter proteins -- Cystic fibrosis : alternative approaches to the treatment of a genetic disease -- Pharmacogenomics -- Transcription factors and gene expression -- Cellular calcium -- Genetic engineering of mice -- Signalling complexes : protein-protein interactions and lipid rafts -- Recombinant proteins and immunotherapeutics.12aMolecular Targeted Therapy.12aPharmacogeneticsxmethods.22aDrug Delivery Systems.22aDrug Discovery.1 aDickenson, John.