02030cam a22004094a 450000100090000000300080000900500170001700800410003401000170007501500190009201600200011101600180013102000260014902000230017503500240019804000570022204200080027905000250028706000150031206000230032708200200035024500960037026000410046630000330050736500160054050400510055650506740060765000220128165000190130365000490132265000290137170000210140070000210142194200120144299900170145495201490147115928530BD-DhUL20150912115821.0090929s2010    njua     b    001 0 eng    a  2009040188  2bnbaGBA9A04287 a1015161102DNLM7 a0153922032Uk  a9780470257616 (cloth)  a047025761X (cloth)  a(OCoLC)ocn435422355  aDNLM/DLCcDLCdYDXdNLMdBTCTAdYDXCPdUKMdDLCdDLC  apcc00aRM301.25b.L433 201000a2010 D-76810aQV 744bL4345 201000a615.19222bRAL00aLead generation approaches in drug discovery /c[edited by] Zoran Rankovic, Richard Morphy.  aHoboken, N.J. :bJohn Wiley,cc2010.  axi, 295 p. :bill. ;c25 cm.  aUS$b106.15  aIncludes bibliographical references and index.0 aLead discovery : the process / William F. Michne -- High throughput screening approach to lead discovery / Zoran Rankovic, Craig Jamieson, and Richard Morphy -- In silico screening / Dagmar Stumpfe, Hanna Geppert, and Jürgen Bajorath -- Fragment-based lead discovery / Jeffrey S. Albert -- Design of multitarget ligands / Richard Morphy and Zoran Rankovic -- De novo drug design / Gisbert Schneider, Markus Hartenfeller, Ewgenij Proschak -- Role of natural products in drug discovery / Hugo Lachance, Stefan Wetzel, and Herbert Waldmann -- Early screening for ADMET properties / Dennis A. Smith -- Role of chemistry in lead discovery / Roland E. Dolle and Karin Worm. 0aDrug development. 0aDrugsxDesign. 0aHigh throughput screening (Drug development)12aDrug Discoveryxmethods.1 aRankovic, Zoran.1 aMorphy, Richard.  2ddccBK  c41576d41576  00102ddc406615_190000000000000_RAL708NFIC968023aDUSLbDUSLcGENd2015-06-18ePurchasedo615.19 RALp492914r2015-09-12t1w2015-09-12yBK