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  <titleInfo>
    <title>Lead generation approaches in drug discovery</title>
  </titleInfo>
  <name type="personal">
    <namePart>Rankovic, Zoran.</namePart>
  </name>
  <name type="personal">
    <namePart>Morphy, Richard.</namePart>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <originInfo>
    <place>
      <placeTerm type="code" authority="marccountry">nju</placeTerm>
    </place>
    <place>
      <placeTerm type="text">Hoboken, N.J</placeTerm>
    </place>
    <publisher>John Wiley</publisher>
    <dateIssued>c2010</dateIssued>
    <dateIssued encoding="marc">2010</dateIssued>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
    <form authority="marcform">print</form>
    <extent>xi, 295 p. : ill. ; 25 cm.</extent>
  </physicalDescription>
  <tableOfContents>Lead discovery : the process / William F. Michne -- High throughput screening approach to lead discovery / Zoran Rankovic, Craig Jamieson, and Richard Morphy -- In silico screening / Dagmar Stumpfe, Hanna Geppert, and Jürgen Bajorath -- Fragment-based lead discovery / Jeffrey S. Albert -- Design of multitarget ligands / Richard Morphy and Zoran Rankovic -- De novo drug design / Gisbert Schneider, Markus Hartenfeller, Ewgenij Proschak -- Role of natural products in drug discovery / Hugo Lachance, Stefan Wetzel, and Herbert Waldmann -- Early screening for ADMET properties / Dennis A. Smith -- Role of chemistry in lead discovery / Roland E. Dolle and Karin Worm.</tableOfContents>
  <note type="statement of responsibility">[edited by] Zoran Rankovic, Richard Morphy.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Drug development</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Drugs</topic>
    <topic>Design</topic>
  </subject>
  <subject authority="lcsh">
    <topic>High throughput screening (Drug development)</topic>
  </subject>
  <subject authority="mesh">
    <topic>Drug Discovery</topic>
    <topic>methods</topic>
  </subject>
  <classification authority="lcc">RM301.25 .L433 2010</classification>
  <classification authority="ddc" edition="22">615.19 RAL</classification>
  <classification authority="nlm">2010 D-768</classification>
  <classification authority="nlm">QV 744 L4345 2010</classification>
  <identifier type="isbn">9780470257616 (cloth)</identifier>
  <identifier type="isbn">047025761X (cloth)</identifier>
  <identifier type="lccn">2009040188</identifier>
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    <recordCreationDate encoding="marc">090929</recordCreationDate>
    <recordChangeDate encoding="iso8601">20150912115821.0</recordChangeDate>
    <recordIdentifier source="BD-DhUL">15928530</recordIdentifier>
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