Lead generation approaches in drug discovery - Rankovic, Zoran; Morphy, Richard (Hoboken, N.J. : John Wiley, 2010)
Lead discovery : the process / William F. Michne -- High throughput screening approach to lead discovery / Zoran Rankovic, Craig Jamieson, and Richard Morphy -- In silico screening / Dagmar Stumpfe, Hanna Geppert, and Jürgen Bajorath -- Fragment-based lead discovery / Jeffrey S. Albert -- Design of multitarget ligands / Richard Morphy and Zoran Rankovic -- De novo drug design / Gisbert Schneider, Markus Hartenfeller, Ewgenij Proschak -- Role of natural products in drug discovery / Hugo Lachance, Stefan Wetzel, and Herbert Waldmann -- Early screening for ADMET properties / Dennis A. Smith -- Role of chemistry in lead discovery / Roland E. Dolle and Karin Worm.
Includes bibliographical references and index.
Keywords: Drug development; Drugs -- Design; High throughput screening (Drug development); Drug Discovery -- methods