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  <titleInfo>
    <title>Aging of the genome</title>
    <subTitle>the dual role of DNA in life and death</subTitle>
  </titleInfo>
  <name type="personal">
    <namePart>Vijg, Jan.</namePart>
    <role>
      <roleTerm authority="marcrelator" type="text">creator</roleTerm>
    </role>
  </name>
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  <originInfo>
    <place>
      <placeTerm type="code" authority="marccountry">enk</placeTerm>
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    <place>
      <placeTerm type="text">Oxford</placeTerm>
    </place>
    <publisher>Oxford University Press</publisher>
    <dateIssued>2007</dateIssued>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
    <form authority="gmd">electronic resource</form>
    <extent>1 online resource (x, 372 p.) : ill.</extent>
  </physicalDescription>
  <abstract>Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the technology has been developed to test this theory and its consequences. This book reviews the concept of genomic instability as a possible universal cause of aging in complex organisms.</abstract>
  <targetAudience authority="marctarget">specialized</targetAudience>
  <note type="statement of responsibility">Jan Vijg.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Aging</topic>
    <topic>Genetic aspects</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Apoptosis</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Genomes</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Developmental genetics</topic>
  </subject>
  <subject authority="lcsh">
    <topic>DNA damage</topic>
  </subject>
  <classification authority="lcc">QP86</classification>
  <classification authority="ddc" edition="22">612.8</classification>
  <relatedItem type="otherFormat" displayLabel="Print version"/>
  <identifier type="isbn">9780191728242 (ebook) :</identifier>
  <identifier type="isbn">0191728241 (ebook) :</identifier>
  <identifier type="uri">http://dx.doi.org/10.1093/acprof:oso/9780198569237.001.0001</identifier>
  <location>
    <url displayLabel="Oxford scholarship online">http://dx.doi.org/10.1093/acprof:oso/9780198569237.001.0001</url>
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    <recordChangeDate encoding="iso8601">20150804193932.0</recordChangeDate>
    <recordIdentifier source="StDuBDS">EDZ0000075928</recordIdentifier>
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