Lemke, Thomas L. Williams, David A. 1938- Foye, William O. text bibliography pau Philadelphia Lippincott Williams & Wilkins c2002 2002 5th ed. monographic eng

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xii, 1114 p. : ill. ; 29 cm. Introduction: Origins of Medicinal Chemistry / William O. Foye -- Pt. I. Principles of Drug Discovery -- Overview: Drug Design and Development: A Perspective / Michael Williams. 1. Natural Products / Alice M. Clark. 2. Drug Design and Relationship of Functional Groups to Pharmacologic Activity / James J. Knittel and Robin M. Zavod. 3. Molecular Modeling and Drug Design / Eric Billings. 4. Receptors and Drug Action / Timothy J. Maher and David A. Johnson. 5. Drug Design Through Enzyme Inhibition / Stephen G. Kerr. 6. Peptide and Protein Drugs / Michael Mokotoff. 7. Physicochemical and Biopharmaceutical Properties of Drug Substances and Pharmacokinetics / Sunil Jambhekar. 8. Drug Metabolism / David A. Williams. 9. U.S. Drug Regulation: An Overview / Douglas J. Pisano -- Pt. II. Pharmacodynamic Agents -- Overview: Drug Receptors: A Perspective / David J. Triggle. 10. Drugs Affecting Cholinergic Neurotransmission / Danny L. Lattin and E. Kim Fifer. 11. Drugs Affecting Adrenergic Neurotransmission / Robert Griffith. 12. Serotonin Receptors and Drugs Affecting Serotonergic Neurotransmission / Richard A. Glennon and Malgorzata Dukat. 13. Local Anesthetics / Matthias C. Lu. 14. Volatile Anesthetics / Timothy J. Maher. 15. Hypnotics / William Soine. 16. Antiseizure Drugs / Barbara W. Leduc. 17. Psychotherapeutic Drugs: Antipsychotic and Anxiolytic Agents / Raymond G. Booth and John L. Neumeyer. 18. Hallucinogens, Stimulants, and Related Drugs of Abuse / Richard A. Glennon. 19. Opioid Analgesics / David S. Fries. 20. Drugs Used to Treat Neuromuscular Disorders: Antiparkinsonian and Spasmolytic Agents / Raymond G. Booth and John L. Neumeyer. 21. Cardiac Agents: Cardiac Glycosides, Antianginal, and Antiarrhythmic Drugs / Ahmed S. Mehanna. 22. Diuretics / Gary O. Rankin. 23. Angiotensin Converting Enzyme Inhibitors, Antagonists and Calcium Blockers / Marc W. Harrold. 24. Central and Peripheral Sympatholytics and Vasodilators / David A. Williams. 25. Antihyperlipoproteinemics and Inhibitors of Cholesterol Biosynthesis / Marc W. Harrold. 26. Antithrombotics, Thrombolytics, Coagulants and Plasma Extenders / Robert B. Palmer. 27. Insulin and Oral Hypoglycemic Drugs / Robert A. Wiley. 28. Adrenocorticoids / Duane D. Miller, Robert W. Brueggemeier and James T. Dalton. 29. Estrogen, Progestins and Androgens / Robert W. Brueggemeier, Duane D. Miller and James T. Dalton. 30. Thyroid Function and Thyroid Drugs / Ali R. Banijamali. 31. Calcium Homeostasis / Robin M. Zavod. 32. Nonsteroidal Anti-Inflammatory Agents / Ronald F. Borne. 33. Antihistamines and Related Antiallergic and Antiulcer Agents / Wendel L. Nelson. 34. Antibiotics and Antimicrobial Agents / Lester A. Mitscher. 35. Antiparasitic Agents / Thomas L. Lemke. 36. Antifungal Drugs / Robert Griffith and Timothy Tracy. 37. Antimycobacterial Agents / Thomas L. Lemke. 38. Cancer and Cancer Chemotherapy / Patrick S. Callery and Peter M. Gannett. 39. Antiviral Agents and Protease Inhibitors / Manohar L. Sethi -- Pt. III. Recent Advances in Drug Discovery. 40. Pharmaceutical Biotechnology / Robert D. Sindelar. 41. Gene Therapy / Ronald E. Reid. 42. Antisense Therapeutic Agents / Marilyn K. Speedie. 43. Selective Estrogen Receptor Modulators / V. Craig Jordan -- pKa Values for Some Drugs and Miscellaneous Organic Acids and Bases; pH Values for Tissue Fluids / David A. Williams. [edited by] David A. Williams, Thomas L. Lemke. Includes bibliographical references and indexes. Pharmaceutical chemistry Chemistry, Pharmaceutical RS403 .P75 2002 615.19 WIF 0683307371 2001050327 BD-DhUL 010921 20150121171945.0 3387298