03053cam a22004698a 45000010008000000030008000080050017000160080041000330100017000740150019000910160020001100160018001300200028001480350023001760350017001990400058002160500024002740600027002980600023003250820016003482450070003642600042004343000032004763650016005084900040005245040051005645050746006155050774013616500022021356500020021576500049021776500029022266500017022556500036022726500034023086500024023426500025023666500031023917000023024228300060024458560078025055456870BD-DhUL20150121170253.0050415s2006 nju b 001 0 eng  a 2005010943 aGBA5592572bnb7 a1012460812DNLM7 a0132510762Uk a1588293467 (alk. paper) a(OCoLC)ocm59147773 a(NNC)5456870 aDNLM/DLCcDLCdNLMdOCLCQdUKMdBAKERdNNC-MdBD-DhUL00aRM301.25b.B56 2005 0aW1bME9616J v.316 200510aQV 744bB6136 200500a615.19bBIO00aBioinformatics and drug discovery /cedited by Richard S. Larson. aTotowa, N.J. :bHumana Press,cc2006. ax, 444 p. :bill. ;c24 cm. aUS$b158.701 aMethods in molecular biology ;v316 aIncludes bibliographical references and index.0 aNew strategies in drug discovery / Eliot H. Ohlstein ... [et al.] -- Basic microarray analysis : strategies for successful experiments / Scott A. Ness -- From microarray to biological networks : analysis of gene expression profiles / Xiwei Wu and T. Gregory Dewey -- Microarray analysis in drug discovery and clinical applications / Siqun Wang and Qiong Cheng -- Ontology-driven approaches to analyzing data in functional genomics / Francisco Azuje, Fatima Al-Shahrour, and Joaquin Dopazo -- Gene evolution and drug discovery / James O. McInerney ... [et al.] -- Standardization of microarray and pharmacogenomics data / Cassey S. Husser ... [et al.] -- Clinical applications of bioinformatics, genomics, and pharmacogenomics / Omer Iqbal --0 aProtein interactions probed with mass spectrometry / Suma Kaveti and John R. Engen -- Discovering new drug targeting sites on flexible multidomain protein kinases : -- Combining segmental isotopic and site-directed spin labeling for NMR dectection of interfacial clefts / Thomas K. Harris -- NMR-based screening methods for drug discovery / Laurel Sillerud and Richard S. Larson -- Receptor binding sites : bioinformatic approaches / Darren R. Flower -- In silico protein design : fitting sequence onto structure / Bassil I. Dahiyat -- Chemical database preparation for compound acquisition or virtual screening / Cristian G. Bolgna, Marius M. Olah, and Tudor I. Oprea -- Bioinformatics platform development : from gene to lead compound / Alexis S. Ivanov ... [et al.]. 0aDrug development. 0aBioinformatics. 0aHigh throughput screening (Drug development) 0aCombinatorial chemistry.12aDrug Design.22aComputational Biologyxmethods.22aDrug Evaluation, Preclinical.22aGenetic Techniques.22aMicroarray Analysis.22aPharmacogeneticsxmethods.1 aLarson, Richard S. 0aMethods in molecular biology (Clifton, N.J.) ;vv. 316.413Table of contentsuhttp://www.loc.gov/catdir/toc/ecip0511/2005010943.html