02565cam a2200337 a 4500 4051968 BD-DhUL 20150121160205.0 951010s1996 auta 000 0 eng d 3718658666 (hardcover) 3718658674 (softcover) (OCoLC)38412131 (OCoLC)ocm38412131 (NNC)4051968 NNC-M NNC-M OrLoB-B BD-DhUL TEX 615.19 A textbook of drug design and development / edited by Povl Krogsgaard-Larsen ... [et al.]. 2nd ed. Australia : Harwood Academic Publishers, c1996. [viii], 543 p. : ill. (some col.) ; 26 cm. GBP 27.00 Includes bibliographical references and index. Ch. 1. Drug Discovery: An Overview / Michael Williams and Eric M. Gordon -- Ch. 2. Structural and Physicochemical Factors in Drug Action / Uli Hacksell -- Ch. 3. Computer-aided Development of Three-dimensional Pharmacophore Models / Tommy Liljefors and Ingrid Pettersson -- Ch. 4. Quantitative Structure-activity Relationships and Experimental Design / Thomas Hogberg and Ulf Norinder -- Ch. 5. Gene Technology in Pharmaceutical Research and Production / Nanni Din, Jens G. L. Petersen, Henrik Dalboge and Soren Carlsen -- Ch. 6. Receptors / Claus Braestrup -- Ch. 7. Radiotracers: Synthesis and Use in Imaging / Christer Halldin and Thomas Hogberg -- Ch. 8. Ion Channels / David J. Triggle -- Ch. 9. Excitatory Amino Acid Receptors / Ulf Madsen -- Ch. 10. Synaptic Mechanisms as Pharmacological Targets: Gaba, Acetylcholine and Histamine / Povl Krogsgaard-Larsen and Bente Frolund -- Ch. 11. Enzymes and Enzyme Inhibitors / Ian Ahnfelt-Ronne -- Ch. 12. Bio-inorganic Chemistry / Ole Jons and Erik Sylvest Johansen -- Ch. 13. Design and Application of Prodrugs / Gitte Juel Friis and Hans Bundgaard -- Ch. 14. Peptides and Peptidomimetics / Kristina Luthman and Uli Hacksell -- Ch. 15. Bioactive Ether-linked Phospholipids: Platelet-activating Factor (PAF) and Analogs / Fred Snyder -- Ch. 16. Classical Antiviral Agents and Design of New Antiviral Agents / Piet Herdewijn and Erik de Clercq -- Ch. 17. Anticancer Agents / Ingrid Kjoller Larsen -- Ch. 18. Drug Development: From Discovery to Marketing / Joseph P. Yevich. Drugs Design. Drug Design. Krogsgaard-Larsen, Povl. Bundgaard, Hans. AUTH TOC ddc BK 34721 34721 0 0 ddc 0 TEX 0 NFIC 64588 DUSL DUSL GEN 2000-01-30 Purchased TEX 389050 2015-01-21 2 2015-01-21 BK