Systems biology and synthetic biology - Fu, Pengcheng; Panke, Sven. (Hoboken, N.J. : John Wiley & Sons, 2009)
1. Introduction / Pengcheng Fu -- 2. Basics of Molecular Biology, Genetic Engineering, and Metabolic Engineering / Michael X. Wang and Huidong Shi -- 3. High-Throughput Technologies and Functional Genomics / Xiu-Feng Wan and Dorothea K. Thompson -- 4. Genomic Signal Processing of DNA Microarray Data for the Enhanced Prediction of Axillary Lymph Node Status of Breast Cancer Tumors / Gordon S. Okimoto -- 5. Recombinant Genomes: Novel Resources for Systems Biology and Synthetic Biology / Mitsuhiro Itaya -- 6. In silico Genome-Scale Metabolic Models: The Constraint-Based Approach and its Applications / Andrew R. Joyce and Bernhard O. Palsson -- 7. Mathematical Modeling of Genetic Regulatory Networks: Stress Responses in Escherichia coli / Delphine Ropers, Hidde de Jong and Johannes Geiselmann -- 8. Synthetic Life: Ethobricks for a New Biology / Jordi Vallverdu and Claes Gustafsson -- 9. Yeast as a Prototype for Systems Biology / Goutham Vemuri and Jens Nielsen -- 10. Construction and Applications of Genome-Scale in silico Metabolic Models for Strain Improvement / Sang Yup Lee, Jin Sik Kim, Hongseok Yun, Tae Yong Kim, Seung Bum Sohn and Hyun Uk Kim -- 11. Synthetic Biology: Putting Engineering into Bioengineering / Matthias Heinemann and Sven Panke -- 12. Rationales of Gene Design and de novo Gene Construction / Marcus Graf, Thomas Schoedl and Ralf Wagner -- 13. Self-Replication in Chemistry and Biology / Philipp Holliger and David Loakes -- 14. The Synthetic Approach for Regulatory and Metabolic Circuits / Wilson W. Wong and James C. Liao -- 15. Synthetic Gene Networks / David Greber and Martin Fussenegger -- 16. The Theory of Biological Robustness and its Implication to Cancer / Hiroaki Kitano -- 17. Nucleic Acid Engineering / Wenlong Cheng, Liang Ding, Hisakage Funabashi, Nokyoung Park, Soong Ho Um, Jianfeng Xu and Dan Luo -- 18. Potential Applications of Synthetic Biology in Marine Microbial Functional Ecology and Biotechnology / Guangyi Wang and Juanita Mathews -- 19. On Fundamental Implications of Systems and Synthetic Biology / Cliff Hooker -- 20. Outstanding Issues in Systems and Synthetic Biology / Pengcheng Fu and Cliff Hooker.
Includes bibliographical references and index.
Keywords: Biotechnology; Genetic engineering; Biological systems; Genetic Engineering -- methods; Molecular Biology -- methods; Genes, Synthetic; Genomics -- methods; Models, Genetic; Systems Biology -- methods