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  <titleInfo>
    <title>Functional neuromarkers for psychiatry : applications for diagnosis and treatment</title>
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  <name type="personal">
    <namePart>Kropotov, �I�U. D. (�I�Uri�i Dmitrievich)</namePart>
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  <genre authority="">Electronic books.</genre>
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    <place>
      <placeTerm type="text">London</placeTerm>
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    <publisher>Elsevier Science</publisher>
    <dateIssued>2016</dateIssued>
    <issuance>monographic</issuance>
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  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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    <extent>1 online resource : illustrations</extent>
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  <tableOfContents>Cover; Title Page; Copyright Page; Contents; Acknowledgments; Introduction; Two recent events that may change psychiatry; Mental illness as a challenge to healthcare systems; DSM and ICD as dictionaries of psychopathology; The hurdles to overcome; From symptoms to neuronal circuits; From "decade of the brain" to "decade of translation"; Concept of biomarker; Neuromarkers and neuroimaging; Endophenotype in psychiatry; Extended endophenotype; Genetic and epigenetic factors; Common psychiatric diseases are not Mendelian disorders; Risk factors; Search for nonpharmaceutical methods of treatment.</tableOfContents>
  <tableOfContents>Training in clinical neuroscienceHuman Brain Indices database as a source of reference; Personal motives; Part 1 -- Methods of Assessing Neuromarkers; Chapter 1.1 -- Theory of Measurement; True and observed scores, errors; Reliability; Validity; Distribution across population; Percentiles and z scores; Sensitivity and specificity; Effect size; Requirements for introducing a neuromarker into clinical practice; Chapter 1.2 -- Psychometrics and Neuropsychological Assessment; Psychological models; Neuropsychological testing; Supervisory attentional system model; Operations of attentional control.</tableOfContents>
  <tableOfContents>Dual mechanisms of cognitive controlGeneral factor; Reaction time; Reaction time variability; Continuous performance tasks; Infraslow fluctuations in performance; Big 5 model; Chapter 1.3 -- Functional Magnetic Resonance Imaging; Talairach atlas; Montreal Neurological Institute atlas; Physical basis of magnetic resonance imaging; Functional magnetic resonance imaging; BOLD response; BOLD infralow fluctuations; 0.1-Hz hemodynamic oscillations; Processing steps in functional imaging; Activation maps of fMRI; Model-dependent correlational methods; Model-free correlational methods.</tableOfContents>
  <tableOfContents>Task-negative and task-positive networksFunctional connectivity and diffuse tensor imaging; Test-retest reliability; fMRI in neurological practice; Challenges for clinical fMRI; Chapter 1.4 -- Positron Emission Tomography; Physical basis of positron emission tomography; Neuroreceptors; Test-retest reliability; Neurotransmitters and receptor imaging in clinics; Chapter 1.5 -- Spontaneous Electroencephalogram; How an electroencephalogram is measured; Montages; Electrical events in the cortex; 10-20 International System; Frequency bands.</tableOfContents>
  <tableOfContents>Electroencephalograms as a reflection of cortical self-regulationVoltage-gated ion channels; Nonbrain events (artifacts) in electroencephalograms; Spectral analysis of electroencephalograms; Interindividual differences; Wavelet transformation; Coherence; Neuronal sources of electrical currents; Intracortical connectivity; Cortical focus and spikes; Volume conductance; Inverse problem: dipole approximation; Inverse problem: nonparametric solutions; Current source density; Blind source separation; Independent component analysis.</tableOfContents>
  <note type="statement of responsibility">Juri D. Kropotov.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Electroencephalography</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Brain</topic>
    <topic>Diseases</topic>
    <topic>Treatment</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Mental illness</topic>
    <topic>Treatment</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>HEALTH &amp; FITNESS</topic>
    <topic>Diseases</topic>
    <topic>General</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Clinical Medicine</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Diseases</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Evidence-Based Medicine</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Internal Medicine</topic>
  </subject>
  <subject authority="fast">
    <topic>Brain</topic>
    <topic>Diseases</topic>
    <topic>Treatment</topic>
  </subject>
  <subject authority="fast">
    <topic>Electroencephalography</topic>
  </subject>
  <subject authority="fast">
    <topic>Mental illness</topic>
    <topic>Treatment</topic>
  </subject>
  <subject authority="mesh">
    <topic>Mental Disorders</topic>
    <topic>diagnosis</topic>
  </subject>
  <subject authority="mesh">
    <topic>Biomarkers</topic>
  </subject>
  <subject authority="mesh">
    <topic>Mental Disorders</topic>
    <topic>therapy</topic>
  </subject>
  <subject authority="mesh">
    <topic>Brain</topic>
    <topic>physiopathology</topic>
  </subject>
  <subject authority="mesh">
    <topic>Electroencephalography</topic>
  </subject>
  <subject authority="mesh">
    <topic>Neuroimaging</topic>
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  <classification authority="lcc">RC386.6.E43</classification>
  <classification authority="ddc" edition="23">616.8047547</classification>
  <classification authority="nlm">2016 G-441</classification>
  <classification authority="nlm">WM 145.5.N4</classification>
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    <titleInfo>
      <title>Functional Neuromarkers for Psychiatry : Applications for Diagnosis and Treatment</title>
    </titleInfo>
    <name>
      <namePart>Kropotov, Juri D.</namePart>
    </name>
    <originInfo>
      <publisher>Saint Louis : Elsevier Science, �2016</publisher>
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  <identifier type="isbn">0124105203</identifier>
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