05712cam a2200589Ii 4500 ocn913513717 OCoLC 20190328114812.0 m o d cr cnu|||unuuu 150709s2015 ne o 001 0 eng d N$T eng rda pn N$T N$T OPELS EBLCP DEBSZ YDXCP IDEBK CDX OCLCF OCLCQ MERUC OCLCQ WRM U3W D6H OCLCQ WYU TKN 914151782 1066493623 9780124115279 (electronic bk.) 0124115276 (electronic bk.) 9780124114982 0124114989 (OCoLC)913513717 (OCoLC)914151782 (OCoLC)1066493623 QD262 SCI 013040 bisacsh 547.2 23 D'Angelo, John, author. Hybrid retrosynthesis : organic synthesis using Reaxys and SciFinder / [electronic resource] John D'Angelo, Michael B. Smith. Amsterdam, Netherlands : Elsevier, 2015 �2015 1 online resource (xvii, 155 pages) text txt rdacontent computer c rdamedia online resource cr rdacarrier Includes index. Vendor-supplied metadata. Front Cover; Hybrid Retrosynthesis; Copyright Page; Contents; Preface; Common Abbreviations; Summary of Reactions in Chapter 8; 1 Disconnections and Synthesis; 1.A The Disconnection Approach; 1.B Functional Group Exchange Reactions; 2 Making Carbon-Carbon Bonds; 3 Computer-Assisted Syntheses; 4 A Hybrid Retrosynthesis Approach; 5 Creative Strategies to Searching for Reagents; 6 Stereochemistry; 7 Molecules of Greater Complexity; 7.A Convergent Syntheses; 7.B Perovskone; 7.C Amphotericin B; 7.D Carbovir; 8 Common Fundamental Reactions in Organic Chemistry. 8.A Functional Group Exchange ReactionsAcetals and Ketals; 1 From Aldehydes or Ketones; Acid Chlorides; 2 From Carboxylic Acids; Alcohols; 3 From Acid Derivatives (acid chlorides, anhydrides, esters); 4 From Alkenes; 5 From Ethers; 6 From Ketones or Aldehydes; Alcohol-Alcohol; Alcohols-Functionalized; 7 From Epoxides or Alkenes; Aldehydes or Ketones; 8 From Acetals; 9 From Alcohols; 10 From Alkenes; 11 From Alkynes; 12 From Diols; 13 From Nitriles; Alkanes; 14 From Alkenes; 15 From Alkyl Halides; 16 From Ketones or Aldehydes; Alkenes; 17 From Alkynes. 18 From Halides, Sulfonate Esters, or Ammonium SaltsAlkyl Halides; Alkynes; 19 From Alkenyl Halides; Amides; 20 From Acid Derivatives; 21 From Nitriles; Amines; 22 From Azides, Imides, and Halides; 23 From Nitriles; 24 From Nitro Compounds; Anhydrides; 25 From Carboxylic Acids and Acid Derivatives; Aryl Halides; Carboxylic Acids; 26 From Acid Derivatives (acid chlorides, anhydrides, esters, amides); 27 From Alcohols; 28 From 1,3-Dicarboxylic Acids; 29 From Nitriles; Dienes; 30 From Aromatics; Dihalides; Diols; 31 From Alkenes; 32 From Epoxides; Enamines; 33 From Ketones or Aldehydes; Epoxides. 34 From Alkenes35 From Halohydrins; Esters; 36 From Carboxylic Acids and Acids Derivatives; 37 From Ketones; Ethers; 38 From Alcohols; Halides (Alkyl); 39 From Alcohols; 40 From Alkanes and Aryls; 41 From Alkenes; 42 From Alkyl Halides; Halides (Alkenyl); 43 From Alkynes; Imines; 44 From Ketones or Aldehydes; Ketals; Ketones or Aldehydes. See Aldehydes; 45 From Alkynes; 46 From Diols; 47 From Ketone-Acids; Nitriles; 48 From Amides; Nitro Compounds; 49 From Aromatics; Organometallics; 50 From Alkyl Halides; Phenols; 51 From Aryl Halides; Phosphonium Salts; 52 From Alkyl Halides; Sulfonic Acids. 53 From Aromatics8.B Carbon-Carbon Bond Forming Reactions; Alcohols; 54 From Acid Derivatives and Organometallics; 55 From Epoxides; 56 From Ketones or Aldehydes and Organometallics; Alcohols-Esters; 57 From Esters; Alcohol-Ketones; Aldehydes and Ketones; 58 From Aldehydes or Ketones and Alkyl Halides; 59 From Organometallics and Dimethylformamide (DMF); Aldehyde-Alkenes; 60 From Allylic Vinyl Ethers; Alkanes; 61 From Alkenes; 62 From Alkyl Halides and Organometallics; Alkenes; 63 From Alkenes and Aryl Halides (Heck reaction); 64 From Alkenes and Dienes; 65 From Dienes. Organic Synthesis and Retrosynthesis: An Applied Approach provides readers with the essential skills they need for both organic synthesis and retrosynthesis, encouraging their practice in real-life problems included within the text. It is designed to supplement existing organic textbooks, not only providing a refresher on organic chemistry, but also taking the subject one-step further by including practical applied examples to try in Reaxys (www.reaxys.com). In addition, the text provides new, applied skills and tools to help users during organic synthesis courses, and is also useful fo. Organic compounds Synthesis. Chemistry, Organic Databases. Chemical reactions Databases. SCIENCE Chemistry Organic. bisacsh Chemical reactions. fast (OCoLC)fst00853176 Chemistry, Organic. fast (OCoLC)fst00853501 Organic compounds Synthesis. fast (OCoLC)fst01047668 Electronic books. Electronic books Databases. Databases. fast (OCoLC)fst01411643 Electronic book. Smith, Michael, 1946 October 17- author. Print version: Smith, Michael B. Hybrid Retrosynthesis : Organic Synthesis using Reaxys and SciFinder. Burlington : Elsevier Science, �2015 9780124114982 ScienceDirect http://www.sciencedirect.com/science/book/9780124114982 247112 247112