03713cam a2200637Ii 4500 ocn908103132 OCoLC 20190328114811.0 m o d cr mn||||||||| 150428s2015 enka ob 001 0 eng d N$T eng rda pn N$T N$T IDEBK UIU YDXCP CDX OCLCF S4S OCLCQ SAV OSU N$T U3W D6H AU@ UKMGB WYU OCLCA MERER OCLCQ GBB688723 bnb GBB531425 bnb 017514141 Uk 017852895 Uk 101663559 DNLM 981862499 1066459614 9780124115255 (electronic bk.) 012411525X (electronic bk.) 9780124115088 (paperback) 012411508X (paperback) (OCoLC)908103132 (OCoLC)981862499 (OCoLC)1066459614 RM301.25 .B53 2015eb 2015 G-397 QV 745 MED 071000 bisacsh 615/.19 23 44.38 bcl Blass, Benjamin E., author. Basic principles of drug discovery and development / [electronic resource] Benjamin E. Blass. Amsterdam : Elsevier/AP, Academic Press is an imprint of Elsevier, 2015 1 online resource (xv, 574 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier Online resource; title from PDF title page (EBSCO, viewed October 9, 2017) Includes bibliographical references. Drug discovery and development: an overview of modern methods and principles -- The drug discovery process: from ancient times to the present day -- Classical targets in drug discovery -- In vitro screening systems -- Medicinal chemistry -- In vitro ADME and In vivo pharmacokinetics -- Animal models of disease states -- Safety and toxicology -- Basics of clinical trials -- Translational medicine and biomarkers -- Organizational considerations and trends in the pharmaceutical industry -- Intellectual property and patents in drug discovery -- Case studies in drug discovery. Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, providing comprehensive explanations of enabling technologies such as high throughput screening, structure based drug design, molecular modeling, pharmaceutical profiling, and translational medicine, all areas that have become critical steps in the successful development of marketable therapeutics. The text introduces the fundamental principles of drug discovery and development, also discussing important drug targets by class, in vitro screening methods, medicin. Drug development. Drugs Design. MEDICAL / Pharmacology. bisacsh Drug development. fast (OCoLC)fst00898670 Drugs Design. fast (OCoLC)fst00898790 Chimie pharmaceutique. ram Chimie bioorganique. ram Pharmacologie mol�eculaire. ram M�edicaments Conception. ram Drug Discovery. Drug Evaluation. Electronic books. Electronic book. Print version: Blass, Benjamin E. Basic principles of drug discovery and development. [Enhanced Credo edition] Amsterdam [Netherlands] ; Boston [Massachusetts] : Elsevier/AP, Academic Press is an imprint of Elsevier, [2015] 9781785397875 (OCoLC)948018410 ScienceDirect http://www.sciencedirect.com/science/book/9780124115088 247078 247078