05744cam a2200541Ia 4500 ocn895422059 OCoLC 20190328114809.0 m o d cr cnu---unuuu 141115s2015 ne a ob 001 0 eng d EBLCP eng pn EBLCP N$T E7B YDXCP VRC OPELS OCLCF UIU OCLCQ IDEBK FEM OCLCQ U3W D6H AU@ 896647516 968001606 969014868 9780128005903 (electronic bk.) 0128005904 (electronic bk.) 1322304602 9781322304601 9780128000700 0128000708 (OCoLC)895422059 (OCoLC)896647516 (OCoLC)968001606 (OCoLC)969014868 QD400.5.S95 SCI 013040 bisacsh 547.59 23 Green synthetic approaches for biologically relevant heterocycles / [electronic resource] edited by Goutam Brahmachari. Amsterdam ; Waltham, Mass. : Elsevier Science, �2015. 1 online resource : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier text file rda Includes bibliographical references and index. Online resource; title from PDF title page (EBSCO, viewed November 20, 2014). Green Synthetic Approaches for Biologically Relevant Heterocycles reviews this significant group of organic compounds within the context of sustainable methods and processes. Each clearly structured chapter features in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles classified on the basis of ring-size and/or presence of heteratoms(s). Techniques covered include microwave heating, ultrasound, ionic liquids, solid phase, solvent-free, heterogeneous catalysis, and aqueous media, along with multi-component reaction strategies. This book also integrates advances in green chemistry research into industrial applications and process developments. Green Synthetic Approaches for Biologically Relevant Heterocycles is an essential resource on green chemistry technologies for academic researchers, R & D professionals, and students working in medicinal, organic, natural product, and agricultural chemistry. Front Cover; Green Synthetic Approaches for Biologically Relevant Heterocycles; Copyright; Dedication; Contents; Contributors; About the Editor; Foreword; Preface; Chapter 1 -- Green Synthetic Approaches for Biologically Relevant Heterocycles: An Overview; 1. INTRODUCTION; 2. AN OVERVIEW OF THE BOOK; 3. CONCLUDING REMARKS; Chapter 2 -- Synthesis of Bioactive Five- and Six-Membered Heterocycles Catalyzed by Heterogeneous Supported Metals; 1. INTRODUCTION; 2. SYNTHESIS OF N-CONTAINING HETEROCYCLES; 3. SYNTHESIS OF OXYGEN-CONTAINING HETEROCYCLES; 4. SYNTHESIS OF SULFUR-CONTAINING HETEROCYCLES. 5. CONCLUDING REMARKSReferences; Chapter 3 -- Transition-Metal-Free Synthesis of Benzo-Fused Five- and Six-Membered Heterocycles Employing Arynes; 1. INTRODUCTION; 2. SYNTHESIS OF FIVE-MEMBERED HETEROCYCLES; 3. SYNTHESIS OF SIX-MEMBERED HETEROCYCLES; 4. SYNTHESIS OF MEDIUM-SIZED HETEROCYCLES; 5. APPLICATIONS OF THE BENZO-FUSED HETEROCYCLES; 6. CONCLUDING REMARKS; References; Chapter 4 -- Metal-Catalyzed Routes for the Synthesis of Furocoumarins and Coumestans; 1. INTRODUCTION; 2. SYNTHETIC ROUTES TO FUROCOUMARIN DERIVATIVES; 3. SYNTHETIC ROUTES TO COUMESTAN DERIVATIVES; 4. CONCLUDING REMARKS. AcknowledgmentsReferences; Chapter 5 -- Green Solvents for Eco-friendly Synthesis of Bioactive Heterocyclic Compounds; 1. INTRODUCTION; 2. HETEROCYCLIC SYNTHESIS IN SUPERCRITICAL CARBON DIOXIDE; 3. HETEROCYCLIC SYNTHESIS IN PEG; 4. HETEROCYCLIC SYNTHESIS IN GLYCEROL; 5. HETEROCYCLIC SYNTHESIS IN GLUCONIC ACID AQUEOUS SOLUTION; 6. HETEROCYCLIC SYNTHESIS IN ETHYL LACTATE; 7. CONCLUDING REMARKS; References; Chapter 6 -- Green Catalytic Synthesis of Heterocyclic Structures Using Carbon Dioxide and Related Motifs; 1. INTRODUCTION; 2. BIOLOGICAL IMPORTANCE OF CO2-BASED HETEROCYCLIC COMPOUNDS. 3. GREEN SYNTHESIS OF 1,3-DIOXOLAN-2-ONES AND 1,3-DIOXAN-2-ONES USING CO24. GREEN SYNTHESIS OF OXAZOLIDINONES AND OXAZODINANONES USING CO2; 5. RELATED HETEROCYCLES INCORPORATING CO2 OR RELATED SYNTHONS; 6. CONCLUDING REMARKS; References; Chapter 7 -- Synthetic Approaches to Small- and Medium-Size Aza-Heterocycles in Aqueous Media; 1. INTRODUCTION; 2. THREE-MEMBERED RING-AZIRIDINES; 3. FOUR-MEMBERED RINGS; 4. FIVE-MEMBERED RINGS; 5. SIX-MEMBERED RINGS; 6. SEVEN-MEMBERED RINGS; 7. CONCLUDING REMARKS; References. CHAPTER 8 -- Green Synthetic Approaches forBiologically Relevant 2-amino-4H-pyransand 2-amino-4H-pyran-Annulated Heterocyclesin Aqueous Media1. INTRODUCTION; 2. SYNTHETIC APPROACHES FOR 2-AMINO-4H-PYRANS AND 2-AMINO-4H-PYRAN-ANNULATED HETEROCYCLES IN WATER AND ETHANOL-WATER MEDIA; 3. CONCLUDING REMARKS; Acknowledgments; References; Chapter 9 -- Sustainable Synthesis of Benzimidazoles, Quinoxalines, and Congeners; 1. INTRODUCTION; 2. METHODS OF SYNTHESIS OF BENZIMIDAZOLES/QUINOXALINES USING GREENER STRATEGIES; 3. CONCLUDING REMARKS; References. Heterocyclic compounds. Green chemistry. SCIENCE Chemistry Organic. bisacsh Green chemistry. fast (OCoLC)fst00912867 Heterocyclic compounds. fast (OCoLC)fst00955736 Electronic books. Brahmachari, Goutam. Print version: 9780128000700 ScienceDirect http://www.sciencedirect.com/science/book/9780128000700 246998 246998