TY - BOOK AU - Vishwakarma, Ajay, AU - Sharpe, Paul, AU - Shi, Songtao, AU - Wang, Xiu-Ping, TI - Stem cell biology and tissue engineering in dental sciences / SN - 9780123977 AV - R857.T55 S74 2015eb U1 - 571.5/38 23 PY - 2015/// CY - London PB - Elsevier Ltd. KW - Tissue engineering KW - Stem cells KW - Dentistry KW - SCIENCE KW - Life Sciences KW - Anatomy & Physiology KW - bisacsh KW - fast KW - Tissue Engineering KW - Stem Cells KW - Biomedical Engineering KW - Electronic books N1 - Includes index; Includes bibliographical references at the end of each chapters and index; Front Cover; Stem Cell Biology and Tissue Engineering in Dental Sciences; Copyright; Contents; List of Contributors; Foreword; Chapter 1: An Introduction to Stem Cell Biology and Tissue Engineering; 1.1. Introduction; 1.2. The emergence of Tissue Engineering and regenerative medicine; 1.3. Research themes underlying Tissue Engineering technology; 1.3.1. Cells; 1.3.2. Biomaterial Scaffolds; 1.3.3. Tissue-Inducing Factors; 1.3.4. Devices and Systems; 1.4. Stem cell-based therapy; 1.4.1. Pure Stem Cell Therapy; 1.4.2. Scaffold-Based Stem Cell Therapy; 1.5. Translational Tissue Engineering; 1.6. ConclusionReferences; Part I: Developmental Biology: A Blueprint for Tissue Engineering; Chapter 2: Developmentally Inspired Regenerative Organ Engineering: Tooth as a Model ; 2.1. Introduction; 2.2. Understanding generation for regeneration strategies: a tooth model; 2.3. Epithelial-mesenchymal interactions during odontogenesis; 2.4. ECM and mechanical forces as regulators of organogenesis; 2.5. Engineering approaches for tooth organ regeneration; 2.6. Conclusion; References; Chapter 3: Extracellular Matrix Molecules; 3.1. Introduction; 3.1.1. Overview; 3.1.2. Extracellular Matrix Proteins3.1.3. Crosslinking; 3.2. Collagens; 3.2.1. Collagen Biosynthesis and Processing; 3.2.2. Fibril-Forming Collagens; 3.2.2.1. Biomineralization; 3.2.3. Fibril-Associated Collagens (FACITs); 3.2.4. Network-Forming Collagens; 3.2.5. Anchoring Fibrils; 3.2.6. Other Collagens; 3.2.7. Collagenopathies; 3.2.7.1. Osteogenesis Imperfecta (OI); 3.2.7.2. Ehlers-Danlos Syndrome; 3.2.7.3. Skeletal Dysplasias and Chondrodysplasias; 3.2.7.4. Other Collagenopathies; 3.3. Glycoproteins; 3.3.1. Fibronectin; 3.3.2. Fibrillins and Latent TGF-�-Binding Proteins (LTBPs); 3.3.2.1. Structural and Functional Properties of Fibrillins and LTBPs3.3.2.2. Fibrillinopathies; 3.3.3. Fibulins; 3.3.4. Other Glycoproteins; 3.3.4.1. Tenascin; 3.3.4.2. The Small Integrin-Binding Ligand N-Linked Glycoproteins (SIBLINGs); 3.3.4.3. Thrombospondins; 3.4. Elastin and Elastic Fibers; 3.4.1. Elastic Fiber Assembly; 3.4.2. Elastin-Associated Pathologies; 3.5. Basement Membranes; 3.5.1. Laminins; 3.5.2. Collagen Type IV; 3.5.3. Basement Membrane Proteoglycans; 3.5.4. Basement Membrane-Associated Pathologies; 3.6. Proteoglycans and Glycosaminoglycans; 3.6.1. Glycosaminoglycans; 3.6.2. Proteoglycans3.6.2.1. Cell Surface Proteoglycans; 3.6.2.2. Modular Proteoglycans; 3.6.2.3. Small Leucine Rich Proteoglycans (SLRPs); 3.7. Concluding Remarks; Acknowledgments; Abbreviations; References; Chapter 4: Cell-Matrix Interactions and Signal Transduction; 4.1. Introduction; 4.1.1. The First Evidence that Matrices Change Cell Behavior; 4.1.2. Integrin and Non-Integrin Receptor Discovery; 4.2. Receptors; 4.2.1. Integrins: Mediators of Cell-Matrix Interactions; 4.2.1.1. Integrin a Subunits; 4.2.1.2. Integrin � Subunits; 4.2.2. Non-Integrin Receptors for ECM Molecules N2 - The editors have compiled basic embryology and developmental biology with keen focus on stem cells, basic cell and matrix biology with relevance to tissue regeneration and repair, biomaterials (including nanotechnology) and current applications in various disciplines of dental science UR - http://www.sciencedirect.com/science/book/9780123971579 ER -