<?xml version="1.0" encoding="UTF-8"?>
<mods xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://www.loc.gov/mods/v3" version="3.1" xsi:schemaLocation="http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-1.xsd">
  <titleInfo>
    <nonSort>An </nonSort>
    <title>introduction to biotechnology : the science, technology and medical applications</title>
  </titleInfo>
  <name type="personal">
    <namePart>Godbey, W. T.</namePart>
    <role>
      <roleTerm authority="marcrelator" type="text">creator</roleTerm>
    </role>
    <role>
      <roleTerm type="text">author.</roleTerm>
    </role>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <genre authority="">Electronic books.</genre>
  <originInfo>
    <place>
      <placeTerm type="code" authority="marccountry">ne</placeTerm>
    </place>
    <dateIssued encoding="marc">2014</dateIssued>
    <copyrightDate encoding="marc">2014</copyrightDate>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
    <form authority="gmd">electronic resource</form>
    <extent>1 online resource : illustrations (chiefly color).</extent>
  </physicalDescription>
  <abstract>An Introduction to Biotechnology is a biotechnology textbook aimed at undergraduates. It covers the basics of cell biology, biochemistry and molecular biology, and introduces laboratory techniques specific to the technologies addressed in the book; it addresses specific biotechnologies at both the theoretical and application levels.</abstract>
  <tableOfContents>Front Cover; An Introduction to Biotechnology: The science, technology and medical applications; Copyright; Contents; List of Figures; List of Tables; Preface; About the Author; Chapter 1. Membranes; 1.1 . Membrane Lipids; 1.2 . Cholesterol; 1.3 . Membrane Proteins; Questions; Chapter 2. Proteins; 2.1 . Amino Acids; 2.1.1 . p K a ; 2.2 . Protein Structure; 2.2.1 . Primary Structure; 2.2.2 . Secondary Structure; 2.2.2.1 . Supersecondary Structure; 2.2.3 . Tertiary Structure; 2.2.4 . Quaternary Structure; 2.3 . The Hydrophobic Effect; 2.4 . A Return to Membranes.</tableOfContents>
  <tableOfContents>2.4.1 . Protein Movement Within the Plasma Membrane2.4.2 . Restriction of Protein Movement Within the Plasma Membrane; 2.4.3 . Protein Isolation Often Involves Detergents; Questions; Related Reading; Chapter 3: Cellular Transport; 3.1 . Membrane Transporters; 3.1.1 . The Sodium/Glucose Symporter; 3.1.2 . Transporters That Control pH; 3.1.2.1 . Examples of Passive Transport to Control pH; 3.1.2.2 . Examples of Active Transport to Control pH: The Proton ATPases; 3.1.2.3 . Lysosomes; 3.1.3 . Another Active Transporter: The Sodium/Potassium ATPase.</tableOfContents>
  <tableOfContents>3.1.4 . Transporters can be Coupled: The Sodium-Driven Calcium Exchanger3.1.5 . ABC Transporters; 3.1.6 . Hydrophilic Molecule Transport and Electrochemical Gradients; 3.1.6.1 . The Nernst Equation; 3.2 . Vesicular Transporters: Endocytosis; 3.2.1 . Phagocytosis; 3.2.2 . Pinocytosis; 3.2.3 . Endocytosis via Clathrin-Coated Pits; 3.3 . Receptor Fates; 3.3.1 . Receptor Recycling: The LDL Receptor; 3.3.2 . Receptor and Ligand Recycling: The Transferrin Receptor; 3.3.3 . Neither Receptor nor Ligand are Recycled: The Opioid Receptor; 3.3.4 . Transcytosis.</tableOfContents>
  <tableOfContents>3.4 . Lysosomes Are for Degradation, But Are They Safe?3.4.1 . Identification of Intracellular Vesicles; Questions; Related Reading; Chapter 4. Genes: The Blueprints for Proteins; 4.1 . Nucleotides and Nucleic Acids; 4.1.1 . The Phosphoribose Backbone; 4.1.2 . Nucleotide Bases, Nucleosides, and Nucleotides; 4.1.3 . DNA Is the Genetic Material; 4.1.4 . Genomic DNA Is Double-stranded; 4.1.5 . DNA Replication Is Semiconservative; 4.2 . From Genes to Proteins; 4.2.1 . Introduction to the Genetic Code; 4.2.1.1 . Degeneracy and Wobble; 4.2.1.1.1 . Ribosomes and Translation.</tableOfContents>
  <tableOfContents>4.2.1.1.2 . Back to Wobble4.2.1.2 . Mutations and Their Effect on Translation; 4.2.2 . Genes; 4.2.2.1 . How Many Genes Are in the Human Genome?; 4.2.2.2 . Phenotypes; 4.2.3 . Transcription; 4.2.3.1 . The Start of Transcription: RNA Polymerase Binds to DNA; 4.2.3.1.1 . Prokaryotes; 4.2.3.1.2 . Eukaryotes; 4.2.3.1.2.1 . The Eukaryotic 5 2 mRNA Cap; 4.2.3.1.2.2 . Splicing; 4.2.3.1.2.3 . The Eukaryotic Poly(A) Tail; 4.2.3.2 . Regulation of Transcription; 4.2.3.2.1 . Promoters and Promoter Elements; 4.2.3.2.1.1 . TATA Box; 4.2.3.2.1.2 . CpG Islands; 4.2.3.2.1.3 . GC Box; 4.2.3.2.1.4 . CAAT Box.</tableOfContents>
  <note type="statement of responsibility">by W.T. Godbey.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Biotechnology</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>SCIENCE</topic>
    <topic>Chemistry</topic>
    <topic>Industrial &amp; Technical</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>TECHNOLOGY &amp; ENGINEERING</topic>
    <topic>Chemical &amp; Biochemical</topic>
  </subject>
  <subject authority="fast">
    <topic>Biotechnology</topic>
  </subject>
  <subject authority="hilcc">
    <topic>Bioengineering</topic>
  </subject>
  <subject authority="hilcc">
    <topic>Mechanical Engineering</topic>
  </subject>
  <subject authority="hilcc">
    <topic>Engineering &amp; Applied Sciences</topic>
  </subject>
  <classification authority="lcc">TP248.2</classification>
  <classification authority="ddc" edition="23">660.6</classification>
  <relatedItem type="otherFormat" displayLabel="Print version:"/>
  <relatedItem type="series">
    <titleInfo>
      <title>Woodhead Publishing series in biomedicine</title>
    </titleInfo>
  </relatedItem>
  <identifier type="isbn">9781908818485</identifier>
  <identifier type="isbn">1908818484</identifier>
  <identifier type="isbn">9781907568282</identifier>
  <identifier type="isbn">190756828X</identifier>
  <identifier type="uri">http://www.sciencedirect.com/science/book/9781907568282</identifier>
  <identifier type="uri">http://www.sciencedirect.com/science/book/9781907568282</identifier>
  <location>
    <url displayLabel="ScienceDirect">http://www.sciencedirect.com/science/book/9781907568282</url>
  </location>
  <location>
    <url displayLabel="ScienceDirect">http://www.sciencedirect.com/science/book/9781907568282</url>
  </location>
  <recordInfo>
    <recordContentSource authority="marcorg">UKMGB</recordContentSource>
    <recordCreationDate encoding="marc">140912</recordCreationDate>
    <recordChangeDate encoding="iso8601">20190328114808.0</recordChangeDate>
    <recordIdentifier source="OCoLC">ocn890939491</recordIdentifier>
    <languageOfCataloging>
      <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
    </languageOfCataloging>
  </recordInfo>
</mods>
