TY - BOOK AU - Rice, Joseph E., TI - Organic chemistry concepts and applications for medicinal chemistry / SN - 1306642388 AV - QD415 U1 - 547 23 PY - 2014/// CY - San Diego, CA PB - Academic Press, an imprint of Elsevier KW - Clinical chemistry KW - Biochemistry KW - Organic compounds KW - fast KW - Organische Chemie KW - gnd KW - Pharmazeutische Chemie KW - Klinische Chemie KW - Chemistry, Clinical KW - Electronic books N1 - Includes bibliographical references and index; Bonding in organic compounds -- The three-dimensional structure of organic compounds -- Functional groups -- Acids and bases -- Partition coefficients -- The nomenclature of cyclic and polycyclic compounds -- Drug metabolism N2 - Organic Chemistry Concepts and Applications for Medicinal Chemistry provides a valuable refresher for understanding the relationship between chemical bonding and those molecular properties that help to determine medicinal activity. This book explores the basic aspects of structural organic chemistry without going into the various classes of reactions. Two medicinal chemistry concepts are also introduced: partition coefficients and the nomenclature of cyclic and polycyclic ring systems that comprise a large number of drug molecules. Given the systematic name of a drug, the reader is guided through the process of drawing an accurate chemical structure. By emphasizing the relationship between structure and properties, this book gives readers the connections to more fully comprehend, retain, apply, and build upon their organic chemistry background in further chemistry study, practice, and exams. Focused approach to review those organic chemistry concepts that are most important for medicinal chemistry practice and understanding Accessible content to refresh the reader's knowledge of bonding, structure, functional groups, stereochemistry, and more Appropriate level of coverage for students in organic chemistry, medicinal chemistry, and related areas; individuals seeking content review for graduate and medical courses and exams; pharmaceutical patent attorneys; and chemists and scientists requiring a review of pertinent material UR - http://www.sciencedirect.com/science/book/9780128007396 ER -