03979cam a2200421Ki 4500 ocn870333919 OCoLC 20190328114807.0 m o d cr cnu---unuuu 140212s2014 mau o 000 0 eng d OPELS eng rda pn OPELS E7B CDX OCLCF OCLCQ U3W D6H AU@ 9780124170346 (electronic bk.) 012417034X (electronic bk.) (OCoLC)870333919 QD262 547.2 23 Roos, Gregory, author. Key chiral auxiliary applications / [electronic resource] Gregory Roos, Murdoch University, Perth, Western Australia. 2nd ed. Waltham, MA : Academic Press, 2014. �2014 1 online resource text txt rdacontent computer c rdamedia online resource cr rdacarrier Key Chiral Auxiliary Applications, Second Edition is a detailed compilation of chiral auxiliary applications organized by type of transformation. Continuing from the most important and relevant auxiliaries described in its predecessor, the three-volume set Compendium of Chiral Auxiliary Applications (2001), as well as advances in the field, the book provides a vital and timely resource for chemists in the field. Each reaction class includes a series of tables and graphical abstracts of real reactions from the literature and patents to enable easy review and comparison of results. This anticipated edition is based on a screening of nearly 40,000 auxiliary reaction applications, with details supplied for the more than 13,000 selected representative entries: synthetic route, reagents, yields, diastereomeric/enantiomeric excesses, and characterization data. Updated and streamlined with more than 60% new material, Key Chiral Auxiliary Applications provides valuable guidance and reliable content for selecting the best auxiliary for a specific asymmetric synthetic transformation. Provides a comprehensive compilation based on nearly 40,000 diverse applications of chiral auxiliaries for selecting the best synthetic route to optically pure compoundsContains over 60% new material with 13,000+ auxiliary applications categorized by reaction type, with reaction details and chemical and optical yields in one unique resource. Front Cover; Key Chiral Auxiliary Applications; Copyright; CONTENTS; ACKNOWLEDGEMENTS; FOREWORD; PREFACE TO THE 2ND EDITION; ABBREVIATIONS; 1.INTRODUCTION; 1.1. BACKGROUND; 1.2. THE CHIRAL AUXILIARY APPROACH; 1.3. THIS COLLECTION; REFERENCES; 2.ALKYLATION AND RELATED REACTIONS I; 2.1 ALLYL AND BENZYL RELATED CARBANIONS; 2.2 ALLENIC ETHER TANDEM ACYLATION-CYCLIZATION; 2.3 ALDEHYDE DERIVED NUCLEOPHILES; 2.4 KETONE DERIVED NUCLEOPHILES; 2.5 ALDEHYDE AND KETONE ENOLATES WITH AUXILIARY-CONTAINING ELECTROPHILES; REFERENCES; 3.ALKYLATION AND RELATED REACTIONS II. 10.ADDITION TO C=N BONDS10.1 REDUCTION OF IMINES, IMINIUM IONS, HYDRAZONES AND OXIMES; 10.2 NUCLEOPHILIC ADDITION; 10.3 RADICAL ADDITION; 10.4 UGI COUPLING; REFERENCES; 11.ADDITION TO C=O BONDS I; 11.1 REDUCTION; 11.2 WITTIG & RELATED OLEFINATION; 11.3 ADDITION OF ORGANOMETALLIC AND RELATED REAGENTS; REFERENCES; 12.ADDITION TO C=O BONDS II; 12.1 ADDITION OF ENOLATES (ALDOL AND RELATED REACTIONS); REFERENCES; 13.ADDITION TO C=O BONDS III; 13.1 ADDITION OF ENOLATES (ALDOL AND RELATED REACTIONS); 13.2 TANDEM REACTIONS; 13.3 RADICAL REACTIONS; REFERENCES; 14. CYCLOADDITIONS I. Asymmetric synthesis. Enantioselective catalysis. Enantiomers. Asymmetric synthesis. fast (OCoLC)fst00819861 Enantiomers. fast (OCoLC)fst00909487 Enantioselective catalysis. fast (OCoLC)fst00909493 Electronic books. ScienceDirect http://www.sciencedirect.com/science/book/9780124170346 246875 246875