Practical Experimental Design and Data Analysis for Genome-Scale RNAi Research / [electronic resource] Zhang, Xiaohua Douglas creator author. text enk 2011 monographic eng

electronic

1 online resource (232 pages) : digital, PDF file(s). This concise, self-contained and cohesive book focuses on commonly used and recently developed methods for designing and analyzing high-throughput screening (HTS) experiments from a statistically sound basis. Combining ideas from biology, computing and statistics, the author explains experimental designs and analytic methods that are amenable to rigorous analysis and interpretation of RNAi HTS experiments. The opening chapters are carefully presented to be accessible both to biologists with training only in basic statistics and to computational scientists and statisticians with basic biological knowledge. Biologists will see how new experiment designs and rudimentary data-handling strategies for RNAi HTS experiments can improve their results, whereas analysts will learn how to apply recently developed statistical methods to interpret HTS experiments. Xiaohua Douglas Zhang. Title from publisher's bibliographic system (viewed on 09 Oct 2015). High throughput screening (Drug development) Small interfering RNA Experimental design RNA Interference RS419.5 .Z43 2011 615/.19 9780511973888 (ebook) http://dx.doi.org/10.1017/CBO9780511973888 http://dx.doi.org/10.1017/CBO9780511973888 UkCbUP 101011 20180107143414.0 CR9780511973888