03682cam a2200637 i 4500 ocn915775232 OCoLC 20171024102454.0 m o d cr ||||||||||| 150803s2015 nju o 001 0 eng 2015030480 9781118914342 (epub) 1118914341 (epub) 9781118819449 (pdf) 1118819446 (pdf) 9781118679678 (cloth) 9781118819586 1118819586 1118679679 (cloth) 9781118679678 (cloth) DEBBG BV043399087 DEBSZ 480371997 (OCoLC)915775232 DLC eng rda DLC OCLCF N$T DG1 YDXCP COO IDEBK CDX EBLCP RECBK DEBBG KSU DEBSZ pcc MAIN HD9665.5 MED 071000 bisacsh 615.1068/5 23 Alex, Alexander A., editor. Attrition in the pharmaceutical industry : reasons, implications, and pathways forward / edited by Alexander A. Alex, C. John Harris, Dennis A. Smith. [electronic resource] Hoboken, New Jersey : John Wiley & Sons, 2015. 1 online resource. text rdacontent computer rdamedia online resource rdacarrier Includes index. Attrition in drug discovery and development / Scott Boyer, Clive Brealey and Andrew M. Davis -- Compound attrition at the pre-clinical phase / Cornelis E.C.A. Hop -- Attrition in phase I / Dennis A. Smith and Thomas A. Baillie -- Compound attrition in phase II/III / Alexander Alex, C. John Harris, Wilma W. Keighley and Dennis A. Smith -- Post-marketing attrition / Dennis A. Smith -- Influence of the regulatory environment on attrition / Robert T. Clay -- Experimental screening strategies to reduce attrition risk / Marie-Claire Peakman, Matthew Troutman, Rose Gonzales and Anne Schmidt -- Medicinal chemistry strategies to prevent compound attrition / J. Richard Morphy -- Influence of phenotypic and target-based screening strategies on compound attrition and project choice / Andrew Bell, Wolfgang Fecke and Christine Williams -- In silico approaches to address compound attrition / Peter Gedeck, Christian Kramer, Richard Lewis -- Current and future strategies for improving drug discovery efficiency / Peter Mbugua Njogu and Kelly Chibale -- Impact of investment strategies, organizational structure and corporate environment on attrition, and future investment strategies to reduce attrition / Geoff Lawton. Description based on print version record and CIP data provided by publisher. Pharmaceutical industry Management. Pharmaceutical industry Capital productivity. Industrial efficiency. Drug development. Drug development. fast (OCoLC)fst00898670 Industrial efficiency. fast (OCoLC)fst00970970 Pharmaceutical industry Capital productivity. fast (OCoLC)fst01767658 Pharmaceutical industry Management. fast (OCoLC)fst01060159 MEDICAL / Pharmacology bisacsh Electronic books. Harris, C. John, editor. Smith, Dennis A., editor. Print version: Alex, Alexander A., editor. Attrition in the pharmaceutical industry Hoboken, New Jersey : John Wiley & Sons, 2015 9781118679678 (DLC) 2015024772 http://onlinelibrary.wiley.com/book/10.1002/9781118819586 Wiley Online Library ddc BK 208132 208132