05358cam a2200577Ia 4500 ocn908080324 OCoLC 20171025082325.0 m o d cr cnu---unuuu 150425s2015 nju ob 001 0 eng d 9781118628003 (electronic bk.) 1118628004 (electronic bk.) 9781118628270 (electronic bk.) 1118628276 (electronic bk.) 1118627989 9781118627983 9781118627983 10.1002/9781118628003 doi DEBBG BV043397747 (OCoLC)908080324 (OCoLC)913737030 (OCoLC)961517236 (OCoLC)962727173 EBLCP eng pn EBLCP N$T E7B YDXCP RECBK IDEBK DG1 CDX COO OCLCF DEBBG EBLCP OCLCQ KSU K6U MAIN QP801.R47 MED 071000 bisacsh MED 075000 bisacsh SCI 036000 bisacsh 612.3/99 23 The retinoids : biology, biochemistry, and disease / edited by Pascal Dollé and Karen Neiderreither. [electronic resource] Hoboken : Wiley, ©2015. 1 online resource (634 pages) text txt rdacontent computer c rdamedia online resource cr rdacarrier Includes index. Includes bibliographical references at the end of each chapters and index. Vitamin A Metabolic and Enzymatic Pathways. Vitamin A Metabolism, Storage and Tissue Delivery Mechanisms / William S Blaner, Yang Li -- Assimilation and Conversion of Dietary Vitamin A into Bioactive Retinoids / Earl H Harrison, Carlo dela Sena's -- Intracellular Storage and Metabolic Activation of Retinoids / Joseph L Napoli, Charles R Krois -- Evolution of the Retinoic Acid Signaling Pathway / Vincent Laudet, Elisabeth Zieger, Michael Schubert -- Biochemistry and Cellular Biology of Retinoic Acid Signaling. Control of Gene Expression by Nuclear Retinoic Acid Receptors / Marilyn Carrier, Cecile Rochette-Egly -- Retinoic Acid Receptor Coregulators in Epigenetic Regulation of Target Genes / Li-Na Wei -- Retinoid Receptors / William Bourguet, Dino Moras -- How the RAR-RXR Heterodimer Recognizes the Genome / Sylvia Urban, Tao Ye, Irwin Davidson -- Retinoid Receptor-Selective Modulators / Marco-Antonio Mendoza-Parra, William Bourguet, Angel R de Lera, Hinrich Gronemeyer -- Use of Retinoid Receptor Ligands to Identify Other Nuclear Receptor Ligands / Marcia I Dawson, Zebin Xia -- The Dual Transcriptional Activity of Retinoic Acid / Noa Noy -- Retinoids, Epigenetic Changes during Stem Cell Differentiation, and Cell Lineage Choice / Lorraine J Gudas -- Retinoic Acid Signaling in Development. Retinoic Acid Signaling and Central Nervous System Development / Malcolm Maden -- The Role of Retinoic Acid in Limb Development / Gregg Duester -- Retinoic Acid Signaling and Heart Development / Stephane Zaffran, Karen Niederreither -- Retinoic Acid in the Developing Lung and Other Foregut Derivatives / Wellington V Cardoso, Felicia Chen -- Retinoic Acid and the Control of Meiotic Initiation / Josephine Bowles, Peter Koopman -- Retinoids and Physiological Functions. Retinoids and the Visual Cycle / Darwin Babino, Johannes von Lintig -- Retinoid Signaling in the Central Nervous System / Peter McCaffery, Wojciech Krezel -- Retinoid Turnover and Catabolism / A Catharine Ross, Reza Zolfaghari -- Retinoids and the Immune System / J Rodrigo Mora, Makoto Iwata -- Retinoic Acid Receptor Signaling in Post-Natal Male Germ Cell Differentiation / Manuel Mark, Norbert B Ghyselinck -- Retinoids, Disease and Therapy. Epidemiology and Prevention of Vitamin A Deficiency Disorders / Keith P West -- Retinoid Pathway Gene Mutations and the Pathophysiology of Related Visual Diseases / Yaroslav Tsybovsky, Krzysztof Palczewski -- Retinoic Acid in Acute Myeloid Leukemias / Hugues de The, Pierre Fenaux -- Advances in the Use of Retinoids in Cancer Therapy and Prevention / Michael J Spinella, Sarah J Freemantle, Ethan Dmitrovsky. The Retinoids: Biology, Biochemistry, and Disease provides an overview and synthesis of the retinoid molecules, from basic biology to mechanisms of diseases and therapy. The book covers retinoic acid signaling from biochemical, genetic, developmental, and clinical perspectives. The text is divided into five parts, the first of which examines vitamin A metabolic and enzymatic pathways. Focus then shifts to the role of retinoic acid signaling in development, and then to retinoids and physiological function. The book concludes with chapters on retinoids, disease and therapy. Print version record. Retinoids. MEDICAL Pharmacology. bisacsh MEDICAL Physiology. bisacsh SCIENCE Life Sciences Human Anatomy & Physiology. bisacsh Retinoids. fast (OCoLC)fst01096230 Electronic books. Dollé, Pascal. Niederreither, Karen. Print version: Dollé, Pascal. Retinoids : Biology, Biochemistry, and Disease. Hoboken : Wiley, ©2015 9781118627983 http://onlinelibrary.wiley.com/book/10.1002/9781118628003 Wiley Online Library ddc BK 208000 208000