Keserü, G. M. editor. Swinney, David Carl editor. text bibliography Electronic books. Electronic books. gw 2015 monographic eng

electronic resource

1 online resource (xxiii, 334 pages) : illustrations (some color) "This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects. Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and other bioactive molecules. It covers all currently used methods, from experimental approaches, such as ITC or SPR, right up to the latest computational methods. Case studies of real-life lead or drug development projects are also included so readers can apply the methods learned to their own projects. Finally, the benefits of a thorough binding mode analysis for any drug development project are summarized in an outlook chapter written by the editors."-- edited by György M. Keserü and David C. Swinney. Includes bibliographical references and index. Drug development Binding sites (Biochemistry) Thermodynamics Pharmacokinetics MEDICAL / Pharmacology Binding sites (Biochemistry) Thermodynamics Drug development Pharmacokinetics Drug Discovery Receptors, Drug Ligands Thermodynamics Pharmacokinetics RM301.25 .T44 2015eb 615.19 W1 ME9613h v.65 2015 QV 745 (OCoLC)910103973 9783527673049 3527673040 9783527673025 3527673024 9783527673032 3527673032 http://onlinelibrary.wiley.com/book/10.1002/9783527673025 http://onlinelibrary.wiley.com/book/10.1002/9783527673025 EBLCP 150328 20171025084459.0 ocn905991359 eng