05883cam a2200817 i 4500 ocn890080333 OCoLC 20171026111747.0 m o d cr ||||||||||| 140904s2014 nju ob 001 0 eng 2014035427 9781118828519 (ePub) 1118828518 (ePub) 9781118828557 (Adobe PDF) 1118828550 (Adobe PDF) 9781118828533 1118828534 1118285913 (cloth) 9781118285916 (cloth) 9781118285916 (cloth) EB00607373 Recorded Books CHBIS 010442499 CHVBK 334087600 NZ1 16078942 DEBBG BV043397103 (OCoLC)890080333 (OCoLC)905984152 (OCoLC)910271757 (OCoLC)910501424 (OCoLC)927508960 966155 EBSCO DLC eng rda pn DLC N$T DG1 OCLCF EBLCP E7B STF COO YDXCP IDEBK OCLCO CDX RECBK OCLCQ OCLCO OCLCQ DEBBG pcc MAIN RD598 WG 300 MED 085000 bisacsh 617.412 23 Atherosclerosis (Wang) Atherosclerosis : risks, mechanisms, therapies / edited by Hong Wang and Cam Patterson. [electronic resource] Hoboken, New Jersey : Wiley Blackwell, [2014] 1 online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier Includes bibliographical references and index. Title Page; Copyright Page; Contents; Contributors; Foreword; Preface; Section I Risk Factors: Old and New; Chapter 1 Lipoproteins; Brief History of Cholesterol and Atherosclerosis; Lipoproteins; LDL and Atherosclerosis; Triglyceride-Rich Lipoproteins and Atherosclerosis; HDL and Atherosclerosis; Summary; References; Chapter 2 Role of Dysglycemia in Atherosclerosis; Introduction; Molecular Mechanisms by Which Dysglycemia Accelerates Atherosclerosis; Dysglycemia and Endothelial Cells; Dysglycemia and Vascular Smooth Muscle Cells; Dysglycemia and Macrophages; Conclusion; Acknowledgments. Mechanisms of Flow-Induced InflammationConclusions; References; Chapter 5 Homocysteine: A Controversial Cardiovascular Risk Factor; Introduction; Epidemiological Studies: Establishment of Homocysteine as a Risk Factor; Animal Models of Hyperhomocysteinemia; Clinical Intervention Trials; Summary and Perspectives; References; Chapter 6 Hypertension as a Risk Factor for Atherosclerosis; Introduction; Evidence Linking Atherosclerosis and Hypertension; Molecular and Cellular Mechanisms Linking Hypertension and Atherosclerosis; Implications for Treatment and Future Directions; References. Chapter 7 The Genetics of Atherosclerosis: From Polymorphisms to PopulationsIntroduction; Lessons from Mendelian Diseases-Familial Hypercholesterolemia; Role for Genetic Diagnosis and Screening; Genetically Isolated Population Studies: Implications for Atherosclerosis in the General Population; GWAS to Identify Atherosclerosis Risk Genes in the General Population; Identification of a Risk Allele Located at 9P21 by GWAS; Technologic Advances and the Future; Conclusion; Acknowledgments; References; Chapter 8 Life Style; Introduction; Lifestyle Factors and Cardiovascular Disease. Lifestyle Factors and Cardiovascular Disease in the YoungPhysical Activity; Diet and Nutrition; Environmental Effects; Ambient Air Pollution; Other Environmental Factors; Summary; References; Section II Cellular Mechanisms; Chapter 9 Endothelial Cells; Introduction; Endothelial Nitric Oxide; Flow and Arterial Shear Stress; Peroxisome Proliferator-Activated Receptor Nuclear Receptor Family; Endothelial Progenitor Cells; Future Directions; References; Chapter 10 Vascular Smooth Muscle Cells; Introduction; SMCS in Atheroma Progression; Extrinsic Control of SMC Biology. Comprehensive and in-depth in its coverage, Atherosclerosis: Cellular, Molecular & Biochemical Mechanism and Novel Therapy reviews the recent progress in atherosclerosis research and offers cutting edge perspectives from experts in the field. Written by an international team of authors including leading physician-scientists, research experts and physicians, chapters are divided into four major sections, covering risk factors, cellular and molecular mechanisms, biochemical mechanisms and novel and future therapeutics. Atherosclerosis: Cellular, Molecular & Biochemical Mechanism and Novel The. Print version record and CIP data provided by publisher. Atherosclerosis. Atherosclerosis Pathophysiology. Atherosclerosis Prevention. Atherosclerosis Treatment. Coronary Artery Disease physiopathology. Coronary Artery Disease prevention & control. Coronary Artery Disease therapy. Atherosclerosis. Cerebrovascular disease. Medicine. MEDICAL Surgery General. bisacsh Atherosclerosis. fast (OCoLC)fst00820004 Atherosclerosis Pathophysiology. fast (OCoLC)fst00820016 Atherosclerosis Prevention. fast (OCoLC)fst00820017 Atherosclerosis Treatment. fast (OCoLC)fst00820020 Electronic books. Wang, Hong, 1956 September 19- editor. Patterson, Cam, editor. Print version: Hoboken, New Jersey : John Wiley & Sons Inc., [2014] 9781118285916 (DLC) 2014034589 http://onlinelibrary.wiley.com/book/10.1002/9781118828533 Wiley Online Library ddc BK 207657 207657