An introduction to high content screening : imaging technology, assay development, and data analysis in biology and drug discovery - Haney, Steven A.; Bowman, Doug, active 2014; Chakravarty, Arijit; Davies, Anthony, active 2014; Shamu, Caroline (Hoboken, New Jersey : John Wiley & Sons Inc., 2015)
Introduction / Steven Haney -- Fluorescence and cell labeling / Anthony Davies, Steven Haney -- Microscopy fundamentals / Steven Haney, Anthony Davies, Doug Bowman -- Image processing / John Bradley, Doug Bowman, Arijit Chakravarty -- Selecting and setting up a high content imaging platform / Craig Furman, Doug Bowman, Anthony Davies, Caroline Shamu, Steven Haney -- Informatics considerations / Jay Copeland, Caroline Shamu -- Basic high content assay development / Steven Haney, Doug Bowman -- Designing metrics for high content assays / Arijit Chakravarty, Steven Haney, Doug Bowman -- Analyzing well-level data / Steven Haney, Arijit Chakravarty -- Analyzing cell level data / Steven Haney, Lin Guey, Arijit Chakravarty -- Designing robust assays / Arijit Chakrivarty, Doug Bowman, Anthony Davies, Caroline Shamu -- Automation and screening / John Donovan, Arijit Chakravarty, Anthony Davies, Steven Haney, Doug Bowman, John Ringling, Ben Knight -- High content analysis for tissue samples / Kristine Burke, Vaishali Sinde, Alice McDonald, Doug Bowman, Arijit Chakrivarty -- Factoring and clustering high content data / Steven Haney, Arijit Chakravarty -- Supervised machine learning / Jeff Palmer, Arijit Chakravarty.
Includes bibliographical references and index.
Print version record and CIP data provided by publisher.
Keywords: Drugs -- Analysis; Drug development; Drug Design; Systems Biology -- methods; Data Interpretation, Statistical; Drug Evaluation, Preclinical -- methods; Image Processing, Computer-Assisted -- methods; Models, Biological; MEDICAL -- Pharmacology; Drug development; Drugs -- Analysis; Electronic books; Electronic books