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  <titleInfo>
    <title>Drug transporters : molecular characterization and role in drug disposition</title>
  </titleInfo>
  <titleInfo type="uniform">
    <title>Drug transporters (2007)</title>
  </titleInfo>
  <name type="personal">
    <namePart>You, Guofeng</namePart>
    <role>
      <roleTerm type="text">editor.</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Morris, Marilyn Emily</namePart>
    <role>
      <roleTerm type="text">editor.</roleTerm>
    </role>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <genre authority="">Electronic books.</genre>
  <genre authority="">Electronic books.</genre>
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    </place>
    <dateIssued encoding="marc">2014</dateIssued>
    <edition>Second edition.</edition>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
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  <tableOfContents>Overview of drug transporter families -- Organic Cation and Zwitterion transporters OCT, OCTN -- Organic anion transporters OAT -- Organic anion transporting polypeptides OATP -- Mammalian peptide transporters PEPT -- The monocarboxylate transporters MCT -- The nucleoside transporters CNT, ENT -- Bile acid transporters -- Multidrug resistance protein P-glycoprotein -- Multidrug resistance-associated proteins MRP -- Breast cancer resistance protein BCRP -- Multidrug and toxin extrusion proteins MATE -- Drug transport in the liver -- Drug transport in the brain -- Drug transport in the kidney -- Drug transport in the intestine -- Drug transport in the placenta -- Experimental approaches to studying drug transport -- Transporters in drug discovery in silico approaches -- Polymorphisms of drug transporters and clinical relevance -- Diet/nutrient interactions with drug transporters -- Clinical relevance drug-drug interactions, pharmacokinetics, pharmacodynamics and toxicity -- Regulatory science perspectives on transporter studies in drug development.</tableOfContents>
  <note type="statement of responsibility">edited by Guofeng You, Marilyn E. Morris.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Carrier proteins</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Drug carriers (Pharmacy)</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>SCIENCE</topic>
    <topic>Life Sciences</topic>
    <topic>Anatomy &amp; Physiology</topic>
  </subject>
  <subject authority="fast">
    <topic>Carrier proteins</topic>
  </subject>
  <subject authority="fast">
    <topic>Drug carriers (Pharmacy)</topic>
  </subject>
  <subject authority="mesh">
    <topic>Biological Transport</topic>
    <topic>physiology</topic>
  </subject>
  <subject authority="mesh">
    <topic>Membrane Transport Proteins</topic>
    <topic>physiology</topic>
  </subject>
  <subject authority="mesh">
    <topic>Pharmacokinetics</topic>
  </subject>
  <subject authority="gnd">
    <topic>Pharmakokinetik</topic>
  </subject>
  <subject authority="gnd">
    <topic>Arzneimittel</topic>
  </subject>
  <subject authority="gnd">
    <topic>Chemische Synthese</topic>
  </subject>
  <subject authority="gnd">
    <topic>Arzneimittelwechselwirkung</topic>
  </subject>
  <classification authority="lcc">R857.B52</classification>
  <classification authority="ddc">571.6/4</classification>
  <classification authority="nlm">QU 120</classification>
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      <publisher>Hoboken, New Jersey : John Wiley &amp; Sons, Inc., [2014]</publisher>
      <edition>Second edition.</edition>
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      <title>Wiley series in drug discovery and development</title>
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  <identifier type="lccn">2014009508</identifier>
  <identifier type="uri">http://onlinelibrary.wiley.com/book/10.1002/9781118705308</identifier>
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    <recordCreationDate encoding="marc">140307</recordCreationDate>
    <recordChangeDate encoding="iso8601">20171031094242.0</recordChangeDate>
    <recordIdentifier source="OCoLC">ocn871966217</recordIdentifier>
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