04309cam a2200745 i 4500 ocn865452421 OCoLC 20171105083259.0 m o d cr ||||||||||| 131213s2014 nju ob 001 0 eng 2013049613 9781118891032 (pdf) 1118891031 (pdf) 9781118891155 (epub) 1118891155 (epub) 9781118852934 (cloth) 9781118891094 1118891090 1118852931 DEBSZ 407739505 NZ1 15592103 NZ1 15920473 CHVBK 334088151 CHBIS 010442073 DEBBG BV042795653 AU@ 000058366806 DEBBG BV043396422 (OCoLC)865452421 (OCoLC)961649425 (OCoLC)962631525 DLC eng rda DLC YDX EBLCP N$T IDEBK DG1 E7B DEBSZ CUS CDX RECBK RRP UBY YDXCP MMU OCLCO COO B24X7 DEBBG pcc MAIN RA1224.2 WK 102 MED 030000 bisacsh MED 076000 bisacsh MED 078000 bisacsh 614.5/94 23 Khetan, Sushil K. Endocrine disruptors in the environment / Sushil K. Khetan. [electronic resource] Hoboken, New Jersey : John Wiley & Sons, Inc., [2014] 1 online resource. text rdacontent computer rdamedia online resource rdacarrier Includes bibliographical references and index. Environmental endocrine disruptors -- Mechanisms of endocrine system function -- Environmental chemicals targeting estrogen signaling pathways -- Anti-androgenic chemicals -- Thyroid-disrupting chemicals -- Activators of PPAR, RXR, AhR, and steroidogenic Factor 1 -- Effects of EDC mixtures -- Environmentally induced epigenetic modifications and transgenerational effects -- Biodegradations and biotransformations of selected examples of EDCs -- Abiotic degradations/transformations of EDCs Through oxidation processes -- Screening and testing programs for EDCs -- Trace contaminants: implications for water quality sustainability -- Policy and regulatory considerations for EDCs -- Green chemistry principles in the designing and screening for safe chemicals and remediation of EDCs. For most of the last decade, the science of endocrine disruption has evolved with more definitive evidence of its damaging potential to health and the environment. This book lists the major environmental chemicals of concern and their mechanism of endocrine disruption including remedial measures for them. Divided into three parts, it begins with an overview of the endocrine system and endocrine disruptors. It then goes on to cover hormone-signaling mechanisms, followed by various broad classes of putative endocrine disruptors, before introducing readers to environmental epigenetic modifications. Part two of the book focuses on removal processes of various EDCs by biotic and abiotic transformation/degradation. The last section consists of four chapters embracing themes on finding solutions to environmental EDCs. -- Edited summary from book. Description based on print version record and CIP data provided by publisher. Endocrine disrupting chemicals Environmental aspects. Endocrine disrupting chemicals Toxicity testing. Endocrine toxicology. Endocrine Disruptors toxicity. Endocrine Disruptors pharmacology. Environmental Pollutants toxicity. Environmental Pollution. MEDICAL Forensic Medicine. bisacsh MEDICAL Preventive Medicine. bisacsh MEDICAL Public Health. bisacsh Electronic books. Electronic books. Print version: Khetan, Sushil K. Endocrine disruptors in the environment Hoboken, New Jersey : John Wiley & Sons, Inc., [2014] 9781118852934 (DLC) 2013047840 http://onlinelibrary.wiley.com/book/10.1002/9781118891094 Wiley Online Library ddc BK 207146 207146