06451cam a2200685 i 4500 ocn862053174 OCoLC 20171105120818.0 m o d cr ||||||||||| 131101s2014 nju ob 001 0 eng 2013043944 9781118444153 (ePub) 1118444159 (ePub) 9781118444092 (Adobe PDF) 1118444094 (Adobe PDF) 9781118444160 (cloth) 9781118444122 1118444124 1118444167 9781118444160 EB00257519 Recorded Books CHBIS 010441985 CHVBK 334094003 DEBSZ 431634939 NZ1 15497375 NZ1 15906652 DEBBG BV043396323 (OCoLC)862053174 (OCoLC)883262616 (OCoLC)960201521 (OCoLC)961625294 (OCoLC)962639604 DLC eng rda DLC YDX EBLCP N$T DG1 E7B CUI YDXCP COO OCLCF NLGGC DEBSZ RECBK OCLCO DEBBG LOA pcc MAIN QP552.W58 QU 55.2 SCI 007000 bisacsh 572/.64 23 Wnt signaling in development and disease : molecular mechanisms and biological functions / [edited by] Stefan Hoppler, Randall T. Moon. [electronic resource] Hoboken, New Jersey : Wiley Blackwell, [2014] 1 online resource. text rdacontent computer rdamedia online resource rdacarrier Includes bibliographical references and index. Machine generated contents note: Part A: Molecular Signaling Mechanisms: from Pathways to Networks -- Chapter 1: Sending of the Wnt signal and its reception at the membrane (an overview) / Xi He, Rik Korswagen -- Chapter 2: Introduction to Wnt Signal transduction in the cytoplasm / Xi He -- Chapter 3: Regulation of gene expression by Wnt signaling in the nucleus (an overview) / Marian Waterman, Ken Cadigan -- Chapter 4: Wnt target genes: Insights from bioinformatics / Ken Cadigan -- Chapter 5: Introduction to [beta]-catenin-independent Wnt signaling pathways / Michael Kuhl, David Strutt -- Chapter 6: Choice and specificity of Wnt signaling pathways / Guido Zaman, Stuart Aaronson -- Chapter 7: The Cell Biology of Wnt signaling / John Wallingford, Kikuchi -- Chapter 8: New insights from proteomic analysis of Wnt signaling / Ben Major -- Chapter 9: New insights about Wnt pathway mechanisms from global siRNA screens / Ram Dasgupta -- Chapter 10: Insights from mathematical modeling on Wnt signaling network / M. Kuhl -- Chapter 11: The evolution of Wnt signaling / Jenifer Croce (David McClay), Thomas Holstein, Linda Holland -- Part B: Selected key molecules in Wnt signaling -- Chapter 12: The Wnt signal / Roel Nusse, Karl Willert -- Chapter 13: Secreted Wnt inhibitors or modulators / Herbert Steinbeisser, Robert Kypta, Masanori Taira, Paola Bovolenta and Javier Lopez-Rios -- Chapter 14: Frizzleds as G-Protein Coupled Receptors / Gunnar Schulte (Craig Malbon and Randall Moon) -- Chapter 15: Dishevelled, at the crossroads of pathways / Mariann Bienz, John Wallinford, Vitezslav Bryja -- Chapter 16: [beta]-catenin, jobs for one protein in signaling and cell adhesion / Jonathan Pettitt, Cara Gottardi, Koni Basler, Bienz -- Chapter 17: Variety of TCF/LEF structure and function in vertebrate Wnt signaling / Mariann Waterman, Hoppler, Bradley Merrill -- Chapter 18: Insights from Structural Analysis of protein-protein interactions by Wnt Pathway Components and functional multi-protein complex formation / Wenqing Xu -- Part C: Wnt Signaling in Embryonic Development and Adult Tissue Homeostasis -- Chapter 19: Wnt signaling in Early embryonic development: From Fertilization To Gastrulation (an introduction) / Stefan Hoppler -- Chapter 20: Wnt signaling in Embryonic Stem Cells: Insights into Early Mammalian Development / Kathy Davidson -- Chapter 21: Wnt signaling specifying Neural Lineages / Corinne Houart, Richard Dorsky -- Chapter 22: Wnt signaling in Heart Organogenesis / Morressey, Hoppler, M. Kuhl -- Chapter 23: Wnt signaling in Kidney organogenesis / Andy McMahon, Seppo Vainio -- Chapter 24: Wnt signaling regulation of tissue architecture (EMT and MET) and morphogenesis / Liz Vincan -- Chapter 25: Wnt Signaling in Tissue Homeostasis in Adults / Elaine Fuchs, Hans Clevers -- Chapter 26: Restoring Tissue Homeostasis: Wnt Signaling in Tissue Regeneration After Acute Injury / Author tbd -- PART D: Wnt Signaling In Chronic Disease -- Chapter 27: Wnt signaling in Disease (an overview) / Randall Moon -- Chapter 28: Wnt signaling in Colorectal Cancer / Paul Polakis or Riccardo Fodde, Owen Sansom -- Chapter 29: Wnt signaling in Melanoma / Andy Chien -- Chapter 30: Wnt signaling in psychiatric disease and dementia / Stephen Haggarty -- Chapter 31: Wnt signaling Therapeutics / Trevor Dale, Randall Moon, et al. "Widely recognized as one of the most important signaling mechanisms in development and disease, Wnt signaling pathways are networks of proteins that play significant roles in embryogenesis or cancer development. Wnt Signaling in Development and Disease addresses the fundamentals of Wnt signaling and delves into molecular pathway mechanisms, its role in embryogenesis, adult tissue homeostasis, and chronic disease. This comprehensive resource details current knowledge of Wnt signaling while looking ahead to future progress"--Provided by publisher. Description based on print version record and CIP data provided by publisher. Wnt Proteins physiology. Wnt proteins. Cellular signal transduction. SCIENCE Life Sciences Biochemistry. bisacsh Cellular signal transduction. fast (OCoLC)fst00850288 Wnt proteins. fast (OCoLC)fst01176458 Electronic books. Electronic books. Hoppler, Stefan, 1965- editor of compilation. Moon, Randall T., editor of compilation. Print version: Wnt signaling in development and disease Hoboken, New Jersey : John Wiley & Sons, [2014] 9781118444160 (DLC) 2013042745 http://onlinelibrary.wiley.com/book/10.1002/9781118444122 Wiley Online Library ddc BK 207067 207067