<?xml version="1.0" encoding="UTF-8"?>
<mods xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://www.loc.gov/mods/v3" version="3.1" xsi:schemaLocation="http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-1.xsd">
  <titleInfo>
    <nonSort>A </nonSort>
    <title>practical guide to designing phase II trials in oncology</title>
  </titleInfo>
  <name type="personal">
    <namePart>Brown, Sarah R.</namePart>
    <role>
      <roleTerm type="text">editor of compilation.</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Gregory, Walter M.</namePart>
    <role>
      <roleTerm type="text">editor of compilation.</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Twelves, Chris</namePart>
    <role>
      <roleTerm type="text">editor of compilation.</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Brown, Julia (Julia M.)</namePart>
    <role>
      <roleTerm type="text">editor of compilation.</roleTerm>
    </role>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <genre authority="">Electronic books.</genre>
  <genre authority="">Electronic books.</genre>
  <originInfo>
    <place>
      <placeTerm type="code" authority="marccountry">enk</placeTerm>
    </place>
    <dateIssued encoding="marc">2014</dateIssued>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
    <form authority="gmd">electronic resource</form>
    <extent>1 online resource.</extent>
  </physicalDescription>
  <abstract>"Choosing Your Phase II Trial Design provides an overview to clinical trial researchers of the steps involved in designing a phase II trial and provides a way to identify a range of optimal designs. Providing a practical guide containing the information needed to make crucial decisions regarding phase II trial designs, it sets forth specific points for consideration between the statistician and clinician when designing a phase II trial, including issues such as how the treatment works, choice of outcome measure and randomisation. A detailed library of trial designs is featured along with examples and case studies accompanied by illustrations using a flow diagram, highlighting the choices made for each key point throughout the process. For those new to trial design, the book provides an introduction to the concepts behind informed decision making in phase II trials, offering a unique and practical learning tool. For those familiar with phase II trial design, the reader will benefit from exposure to new, less familiar trial designs, providing alternative options to those which the reader may not have previously used"--Provided by publisher.</abstract>
  <note type="statement of responsibility">[edited by] Sarah R. Brown, Walter M. Gregory, Christopher Twelves, Julia Brown.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="mesh">
    <topic>Clinical Trials, Phase II as Topic</topic>
  </subject>
  <subject authority="mesh">
    <topic>Antineoplastic Agents</topic>
    <topic>therapeutic use</topic>
  </subject>
  <subject authority="mesh">
    <topic>Drug Evaluation</topic>
    <topic>methods</topic>
  </subject>
  <subject authority="mesh">
    <topic>Neoplasms</topic>
    <topic>drug therapy</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Clinical trials</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Antineoplastic agents</topic>
    <topic>Therapeutic use</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Tumors</topic>
    <topic>Treatment</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>HEALTH &amp; FITNESS</topic>
    <topic>Diseases</topic>
    <topic>General</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Clinical Medicine</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Diseases</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Evidence-Based Medicine</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Internal Medicine</topic>
  </subject>
  <subject authority="fast">
    <topic>Antineoplastic agents</topic>
    <topic>Therapeutic use</topic>
  </subject>
  <subject authority="fast">
    <topic>Clinical trials</topic>
  </subject>
  <subject authority="fast">
    <topic>Tumors</topic>
    <topic>Treatment</topic>
  </subject>
  <subject>
    <topic>Clinical Trials, Phase II as Topic</topic>
  </subject>
  <classification authority="lcc">RC271.C5</classification>
  <classification authority="ddc" edition="23">616.99/4061</classification>
  <classification authority="nlm">QV 771.4</classification>
  <relatedItem type="otherFormat" displayLabel="Print version:">
    <titleInfo>
      <title>Practical guide to designing phase II trials in oncology</title>
    </titleInfo>
    <originInfo>
      <publisher>Chichester, West Sussex : John Wiley &amp; Sons Inc., 2014</publisher>
    </originInfo>
    <identifier type="local">(DLC)  2013041156</identifier>
  </relatedItem>
  <relatedItem type="series">
    <titleInfo>
      <title>Statistics in practice</title>
    </titleInfo>
  </relatedItem>
  <identifier type="isbn">9781118763636 (ePub)</identifier>
  <identifier type="isbn">1118763637 (ePub)</identifier>
  <identifier type="isbn">9781118763629 (Adobe PDF)</identifier>
  <identifier type="isbn">1118763629 (Adobe PDF)</identifier>
  <identifier type="isbn" invalid="yes"/>
  <identifier type="isbn">9781118763612</identifier>
  <identifier type="isbn">1118763610</identifier>
  <identifier type="isbn">1118570901</identifier>
  <identifier type="isbn">9781118570906</identifier>
  <identifier type="isbn">9781306546898</identifier>
  <identifier type="isbn">1306546893</identifier>
  <identifier type="lccn">2013043516</identifier>
  <identifier type="uri">http://onlinelibrary.wiley.com/book/10.1002/9781118763612</identifier>
  <location>
    <url>http://onlinelibrary.wiley.com/book/10.1002/9781118763612</url>
  </location>
  <recordInfo>
    <recordContentSource authority="marcorg">DLC</recordContentSource>
    <recordCreationDate encoding="marc">131030</recordCreationDate>
    <recordChangeDate encoding="iso8601">20171106082003.0</recordChangeDate>
    <recordIdentifier source="OCoLC">ocn861966489</recordIdentifier>
    <languageOfCataloging>
      <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
    </languageOfCataloging>
  </recordInfo>
</mods>
