04657cam a2200925 i 4500 ocn861966489 OCoLC 20171106082003.0 m o d cr ||||||||||| 131030s2014 enk ob 001 0 eng 2013043516 9781118763636 (ePub) 1118763637 (ePub) 9781118763629 (Adobe PDF) 1118763629 (Adobe PDF) 9781118570906 (hardback) 9781118763612 1118763610 1118570901 9781118570906 9781306546898 1306546893 CHBIS 010259581 CHVBK 325944229 NZ1 15581352 DEBSZ 423179748 NZ1 15906857 NZ1 16092524 GBVCP 813893275 DEBBG BV043396313 (OCoLC)861966489 (OCoLC)927508965 (OCoLC)961619204 (OCoLC)962565629 DLC eng rda DLC N$T IDEBK E7B CUS DG1 YDXCP CDX OCLCF COO DEBSZ OCLCO EBLCP DEBBG pcc MAIN RC271.C5 QV 771.4 HEA 039000 bisacsh MED 014000 bisacsh MED 022000 bisacsh MED 112000 bisacsh MED 045000 bisacsh 616.99/4061 23 A practical guide to designing phase II trials in oncology / [edited by] Sarah R. Brown, Walter M. Gregory, Christopher Twelves, Julia Brown. [electronic resource] Chichester, West Sussex : John Wiley & Sons Inc., 2014. 1 online resource. text rdacontent computer rdamedia online resource rdacarrier Statistics in practice Includes bibliographical references and index. "Choosing Your Phase II Trial Design provides an overview to clinical trial researchers of the steps involved in designing a phase II trial and provides a way to identify a range of optimal designs. Providing a practical guide containing the information needed to make crucial decisions regarding phase II trial designs, it sets forth specific points for consideration between the statistician and clinician when designing a phase II trial, including issues such as how the treatment works, choice of outcome measure and randomisation. A detailed library of trial designs is featured along with examples and case studies accompanied by illustrations using a flow diagram, highlighting the choices made for each key point throughout the process. For those new to trial design, the book provides an introduction to the concepts behind informed decision making in phase II trials, offering a unique and practical learning tool. For those familiar with phase II trial design, the reader will benefit from exposure to new, less familiar trial designs, providing alternative options to those which the reader may not have previously used"--Provided by publisher. Description based on print version record and CIP data provided by publisher. Clinical Trials, Phase II as Topic. Antineoplastic Agents therapeutic use. Drug Evaluation methods. Neoplasms drug therapy. Clinical trials. Antineoplastic agents Therapeutic use. Tumors Treatment. HEALTH & FITNESS Diseases General. bisacsh MEDICAL Clinical Medicine. bisacsh MEDICAL Diseases. bisacsh MEDICAL Evidence-Based Medicine. bisacsh MEDICAL Internal Medicine. bisacsh Antineoplastic agents Therapeutic use. fast (OCoLC)fst00810609 Clinical trials. fast (OCoLC)fst00864429 Tumors Treatment. fast (OCoLC)fst01158791 Clinical Trials, Phase II as Topic. Electronic books. Electronic books. Brown, Sarah R., editor of compilation. Gregory, Walter M., editor of compilation. Twelves, Chris, editor of compilation. Brown, Julia (Julia M.), editor of compilation. Print version: Practical guide to designing phase II trials in oncology Chichester, West Sussex : John Wiley & Sons Inc., 2014 9781118570906 (DLC) 2013041156 Statistics in practice. http://onlinelibrary.wiley.com/book/10.1002/9781118763612 Wiley Online Library ddc BK 207059 207059