Hiraku, Yūsuke editor. Kawanishi, Shōsuke 1942- editor. Ōshima, Hiroshi 1949- editor. text bibliography Electronic books. Electronic books. nju 2014 monographic eng

electronic resource

1 online resource (xvi, 383 pages) : illustrations Titlepage; Copyright; Contents; CONTRIBUTORS; PREFACE; CHAPTER 1 INFECTION, INFLAMMATION, AND CANCER: OVERVIEW; INFECTION, INFLAMMATION, AND CANCER: POSSIBLE MECHANISMS; PRODUCTION OF INFLAMMATORY MEDIATORS AND REACTIVE OXIDANTS; DNA AND PROTEIN DAMAGE BY ROSs AND RNSs; INFLAMMATION, EPIGENETIC MODIFICATION, AND microRNA; CONCLUDING REMARKS; REFERENCES; CHAPTER 2 STEM CELL THEORY AND INFLAMMATION-RELATED CANCER; CHRONIC INFLAMMATION AND CANCER; CANCER STEM CELLS; CARCINOGENIC FACTORS ARISING FROM CHRONIC INFLAMMATION; CHRONIC INFLAMMATION AND NORMAL STEM CELL FUNCTION Inflammation and the development and regulation of cancer stem cellsconcluding remarks; references; chapter 3 epithelial-mesenchymal transition: a link between cancer and inflammation; emt: a link between cancer and inflammation; q1: how are emt-permissive, inflammatory tumor microenvironments created?; q2: which emt-promoting signals are provided by inflammatory tumor microenvironments?; q3: how do emt-promoting signals influence the migratory behavior of tumor cells?; conclusions and future prospects; references; chapter 4 role of nitrative dna damage in inflammation- related carcinogenesis Dna damage during chronic inflammationliver fluke-induced cholangiocarcinoma; hpv-induced cervical cancer; ebv-induced nasopharyngeal carcinoma; dna damage induced by asbestos exposure; dna damage induced by carbon nanotube; soft tissue tumors and prognosis of tumor patients; conclusions and future prospects; references; chapter 5 lipid peroxidation-derived dna adducts and the role in inflammation-related carcinogenesis; lpo-derived reactive products contribute to dna damage; results and discussion; conclusions and future prospects; references CHAPTER 6 LEVEL OF INFLAMMATION-RELATED DNA ADDUCTS IN HUMAN TISSUESLEVEL OF 4-ONE- AND 4-OHE-DERIVED DNA ADDUCTS IN HUMAN TISSUES; BIOLOGICAL PROPERTIES OF 4-ONE- AND 4-OHE-DERIVED DNA ADDUCTS; INFLAMMATION AND FORMATION OF 4-ONE; CONCLUDING REMARKS; REFERENCES; CHAPTER 7 TOLL-LIKE RECEPTORS: ROLE IN INFLAMMATION AND CANCER; TLRs AND THEIR LIGANDS; TLR SIGNALING; MYD88-DEPENDENT SIGNALING PATHWAYS; TRIF-DEPENDENT SIGNALING PATHWAYS; INNATE IMMUNE CELLS IN CANCER TISSUES; TLRs AND TUMOR MICROENVIRONMENT; TOLL-LIKE RECEPTORS IN CANCER AND TUMOR THERAPY; ANTITUMOR ACTIVITY OF TLR LIGANDS ROLES OF TLRs IN CANCER PROGRESSIONCURRENT AND FUTURE DEVELOPMENTS; REFERENCES; CHAPTER 8 INFLAMMASOMES AND INFLAMMATION; NOD-LIKE RECEPTORS AND THE INFLAMMASOMES; THE NLRP3 INFLAMMASOME; THE IPAF INFLAMMASOME; THE NLRP1 INFLAMMASOME; THE NLRP12 INFLAMMASOME; THE NLRP7 INFLAMMASOME; THE NLRP6 INFLAMMASOME; THE AIM2 INFLAMMASOME; CYTOKINE TARGETS OF THE INFLAMMASOME; INFLAMMASOME DYSREGULATION IN DISEASE; CONCLUDING REMARKS; REFERENCES; CHAPTER 9 ACTIVATION-INDUCED CYTIDINE DEAMINASE: AN INTRINSIC GENOME MODULATOR IN INFLAMMATION-ASSOCIATED CANCER DEVELOPMENT edited by Dr. Yusuke Hiraku, Dr. Shosuke Kawanishi, Dr. Hiroshi Ohshima. Includes index. Includes bibliographical references and index. Carcinogenesis Inflammation Mediators Inflammation Immunological aspects Cancer Immunological aspects Neoplasms genetics HEALTH & FITNESS Diseases General MEDICAL Clinical Medicine MEDICAL Diseases MEDICAL Evidence-Based Medicine MEDICAL Internal Medicine Cancer Immunological aspects Carcinogenesis Inflammation Immunological aspects Inflammation Mediators Inflammation - Immunological aspects RC268.5 616.99/401 QZ 202 Hoboken, New Jersey : Wiley, [2014] (DLC) 2013035524 (OCoLC)859252945 9781118826553 1118826558 9781118826676 1118826671 9781118826621 1118826620 9781306533058 1306533058 2013039801 http://onlinelibrary.wiley.com/book/10.1002/9781118826621 http://onlinelibrary.wiley.com/book/10.1002/9781118826621 DLC 130930 20171106082828.0 ocn859253561 eng