03966cam a2200721Ii 4500 ocn858861712 OCoLC 20171106083115.0 m o d cr cnu---unuuu 130924s2013 nju ob 001 0 eng d 9781118660379 (ePDF) 1118660374 (ePDF) 9781118179796 111817979X 9781118659984 (epub) 1118659988 (epub) 9781118660409 (emobi) 1118660404 (emobi) 9781118660485 111866048X AU@ 000052334807 NZ1 15340181 DEBBG BV041572424 NLGGC 369354931 AU@ 000052749422 DEBBG BV043396228 (OCoLC)858861712 (OCoLC)862828741 (OCoLC)961559519 (OCoLC)962711076 N$T eng rda pn N$T E7B CUS WAU CDX COO NLGGC YDXCP EBLCP K6U OCLCF DEBBG MAIN RS380 QV 35 MED 071000 bisacsh 615/.19 23 Ho, Rodney J. Y. Biotechnology and biopharmaceuticals : transforming proteins and genes into drugs / Rodney J.Y. Ho and Milo Gibaldi. [electronic resource] Second edition. Hoboken, New Jersey : Wiley Blackwell, [2013] ©2013 1 online resource (xxvi, 698 pages) text txt rdacontent computer c rdamedia online resource cr rdacarrier Includes bibliographical references and index. Introduction to biopharmaceuticals -- Distinctions of biologic versus small molecule platforms in drug development -- Financing biologic drug development -- Application of biotechnology in drug discovery and early development -- Large-scale production of recombinant proteins -- Clinical pharmacology, toxicology, and therapeutic dosage & response -- Clinical evaluation and regulatory approval & enforcement of biopharmaceuticals -- Pharmacoeconomics and drug pricing / Garrison -- Antibodies and derivatives -- Hematopoietic growth and coagulation factors -- Cytokines and interferons -- Hormones -- Enzymes -- Vaccines / Hu, Ho -- Other biopharmaceutical products -- Advances in personalized medicine : pharmacogenetics in drug therapy -- Gene and cell therapy -- Pharmacoeconomics, outcome, and health technology assessment research in drug development -- Summary and future prospects. Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs, Second Edition addresses the pivotal issues relating to translational science, including preclinical and clinical drug development, regulatory science, pharmaco-economics and cost-effectiveness considerations. The new edition also provides an update on new proteins and genetic medicines, the translational and integrated sciences that continue to fuel the innovations in medicine, as well as the new areas of therapeutic development including cancer vaccines, stem cell therapeutics, and cell-based therapies. Description based on print version record. Pharmaceutical biotechnology. MEDICAL / Pharmacology bisacsh Biopharmaceutics. Chemistry, Pharmaceutical. Drug Design. Biopharmaceutics. Chemistry, Pharmaceutical. Drug design. Pharmaceutical biotechnology. fast (OCoLC)fst01060106 Electronic books. Electronic books. Gibaldi, Milo. Print version: Ho, Rodney J. Y. Biotechnology and biopharmaceuticals. Second edition 9781118179796 (DLC) 2013006645 (OCoLC)828334052 http://onlinelibrary.wiley.com/book/10.1002/9781118660485 Wiley Online Library ddc BK 206995 206995