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  <titleInfo>
    <title>Antibiotics : targets, mechanisms and resistance</title>
  </titleInfo>
  <name type="personal">
    <namePart>Gualerzi, Claudio O.</namePart>
    <namePart type="date">1942-</namePart>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <genre authority="">Electronic books.</genre>
  <originInfo>
    <place>
      <placeTerm type="code" authority="marccountry">gw</placeTerm>
    </place>
    <place>
      <placeTerm type="text">Weinheim, Germany</placeTerm>
    </place>
    <publisher>Wiley-VCH</publisher>
    <dateIssued>©2014</dateIssued>
    <dateIssued encoding="marc">2014</dateIssued>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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  <physicalDescription>
    <form authority="gmd">electronic resource</form>
    <extent>1 online resource (xxiv, 549 pages) : illustrations (some color)</extent>
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  <tableOfContents>A chemist's survey of different antibiotic classes -- Antibacterial discovery: problems and possibilities -- Impact of microbial natural products on antibacterial drug discovery -- Antibiotics and resistance: a fatal attraction -- Fitness costs of antibiotic resistance -- Inhibitors of cell-wall synthesis -- Inhibitors of bacetrial cell partitioning -- The membrane as a novel target site for antibiotics to kill persisting bacterial pathogens -- Bacterial membrane, a key for controlling drug influx and efflux -- Interference with bacterial cell-to-cell chemical signaling in development of new anti-infectives -- Recent developments in inhibitors of bacterial type IIA topoisomerases -- Antibiotics targeting bacterial RNA polymerase -- Inhibitors targeting riboswitches and ribozymes -- Targeting ribonuclease P -- Involvement of ribosome biogenesis in antibiotic functions, acquired resistance, and future opportunities in drug discovery -- Aminoacyl-tRNA synthetase inhibitors -- Antibiotics targeting translation initiation in prokaryotes -- Inhibitors of bacterial elongation factor EF-Tu -- Aminoglycoside antibiotics: structural decoding of inhibitors targeting the ribosomal decoding A site -- Reptidyltransferase inhibitors of the bacterial ribosome -- Antibiotics inhibiting the translocation step of protein elongation on the ribosome -- Antibiotics at the ribosomal exit tunnel -- selected structual aspects -- Targeting HSP70 to fight cancer and bad bugs: one and the same battle?</tableOfContents>
  <note type="statement of responsibility">edited by Claudio O. Gualerzi [and others].</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Antibiotics</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Antibiotics</topic>
    <topic>Physiological effect</topic>
  </subject>
  <subject authority="mesh">
    <topic>Anti-Bacterial Agents</topic>
  </subject>
  <subject authority="fast">
    <topic>Antibiotics</topic>
  </subject>
  <subject authority="fast">
    <topic>Antibiotics</topic>
    <topic>Physiological effect</topic>
  </subject>
  <classification authority="lcc">RM267</classification>
  <classification authority="ddc" edition="23">615.7/922</classification>
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    <titleInfo>
      <title>Antibiotics</title>
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    <originInfo>
      <publisher>Weinheim : Wiley-VCH, 2013</publisher>
    </originInfo>
    <identifier type="local">(OCoLC)856201915</identifier>
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  <identifier type="isbn">9783527659685</identifier>
  <identifier type="isbn">3527659684</identifier>
  <identifier type="isbn">1299854656</identifier>
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  <identifier type="isbn">9783527659715</identifier>
  <identifier type="isbn">3527659714</identifier>
  <identifier type="isbn">9783527333059</identifier>
  <identifier type="isbn">3527333053</identifier>
  <identifier type="stock number">516716 MIL</identifier>
  <identifier type="uri">http://onlinelibrary.wiley.com/book/10.1002/9783527659685</identifier>
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    <recordIdentifier source="OCoLC">ocn858657953</recordIdentifier>
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