04899cam a2200697Ii 4500 ocn857365390 OCoLC 20171106090201.0 m o d cr ||||||||||| 130831t20132014gw af ob 001 0 eng d 9783527665785 (electronic bk.) 3527665781 (electronic bk.) 9783527665815 (electronic bk.) 3527665811 (electronic bk.) 9783527665808 (ePub) 3527665803 (ePub) 9783527665792 (Mobi) 352766579X (Mobi) 9781299830240 (MyiLibrary) 1299830242 (MyiLibrary) 9783527333875 3527333878 (hbk.) 9783527333875 (hbk.) AU@ 000052185307 CHBIS 010131681 CHVBK 314710647 DEBSZ 431491003 NZ1 15340131 (OCoLC)857365390 (OCoLC)861745523 (OCoLC)867190737 (OCoLC)898613211 (OCoLC)915719420 (OCoLC)960202377 (OCoLC)961667848 (OCoLC)962584475 514275 MIL EBLCP eng rda pn EBLCP IDEBK CUS MHW DG1 N$T COO YDXCP IUL CDX OCLCO RECBK MEU N15 OCLCF DEBSZ OCLCO OCLCQ OCLCO LOA OCLCO OCLCQ OCLCO MAIN QD461 SCI 016000 bisacsh 548.478 Synthetic methods for biologically active molecules : exploring the potential of bioreductions / edited by Elisabetta Brenna. [electronic resource] Weinheim, Germany : Wiley-VCH, 2013. ©2014 1 online resource (xviii, 387 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier Includes bibliographical references and index. Development of Sustainable Biocatalytic Reduction Processes for Organic Chemists / Roland Wohlgemuth -- Reductases: From Natural Diversity to Established Biocatalysis and to Emerging Enzymatic Activities / Elena Fernández-Álvaro, Pablo Domínguez de María -- Synthetic Strategies Based on C=C Bioreductions for the Preparation of Biologically Active Molecules / Francesco G Gatti, Fabio Parmeggiani, Alessandro Sacchetti -- Synthetic Strategies Based on C=O Bioreductions for the Preparation of Biologically Active Molecules / Aníbal Cuetos, Alba Díaz-Rodríguez, Iván Lavandera -- Protein Engineering: Development of Novel Enzymes for the Improved Reduction of C=C Double Bonds / Sabrina Kille, Manfred T Reetz -- Protein Engineering: Development of Novel Enzymes for the Improved Reduction of C=O Double Bonds / Nobuya Itoh, Yoshihide Makino -- Synthetic Applications of Aminotransferases for the Preparation of Biologically Active Molecules / Sachin Pannuri, Sanjay Kamat, Abraham R Mártin-García -- Strategies for Cofactor Regeneration in Biocatalyzed Reductions / Selin Kara, Joerg H Schrittwieser, Frank Hollmann -- Solvent Effects in Bioreductions / Yan Ni, Hui-Lei Yu, Jian-He Xu -- Application of Product Removal (ISPR) Technologies for Implementation and Scale-Up of Biocatalytic Reductions / John M Woodley -- Bioreductions in Multienzymatic One-Pot and Cascade Processes / Daniela Monti, Erica E Ferrandi -- Dynamic Kinetic Resolutions Based on Reduction Processes / Dimitris Kalaitzakis, Ioulia Smonou -- Relevant Practical Applications of Bioreduction Processes in the Synthesis of Active Pharmaceutical Ingredients / Gábor Tasnádi, Mélanie Hall. This ready reference focuses on the currently available toolbox of biocatalysed reductions of C=O, C=C and formal C=N double bonds to show which transformations are reliable for use in manufacturing processes and which still require improvements and investigation. Following an introductory chapter, chapters 2-4 present the synthetic strategies which are currently available for the reduction of C=C, C=O and for reductive amination, by means of whole cell catalysts and isolated enzymes. Text in English. Online resource; title from PDF title page (Wiley, viewed September 24, 2013). Reduction (Chemistry) Bioactive compounds Synthesis. Enzymes Biotechnology. Enzymes Industrial applications. SCIENCE Physics Crystallography. bisacsh Biochemistry. fast (OCoLC)fst00831961 Biomolecules. fast (OCoLC)fst00832624 Electronic books. Brenna, Elisabetta. Print version: Synthetic methods for biologically active molecules. Weinheim : Wiley-VCH, 2013 9783527333875 (OCoLC)856201927 http://onlinelibrary.wiley.com/book/10.1002/9783527665785 Wiley Online Library ddc BK 206968 206968