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  <titleInfo>
    <title>Methods and applications of statistics in clinical trials</title>
  </titleInfo>
  <name type="personal">
    <namePart>Balakrishnan, N.</namePart>
    <namePart type="date">1956-</namePart>
    <role>
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  <genre authority="">Electronic books.</genre>
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    <dateIssued encoding="marc">2014</dateIssued>
    <issuance>monographic</issuance>
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    <extent>1 online resource (2 volumes).</extent>
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  <abstract>"This comprehensive book features both new and established material on the key statistical principles and concepts for designing modern-day clinical trials, such as hazard ratio, flexible designs, confounding, covariates, missing data, and longitudinal data. It discusses the various kinds of trials that can be found in today's clinical setting including open-labeled trials, multicentered trials, and superiority trials. It also explores such ongoing, cutting-edge trials as early cancer &amp; heart disease, mother to child human immunodeficiency virus transmission, women's health initiative dietary, and AIDS"--Provided by publisher.</abstract>
  <tableOfContents>Volume 1. Concepts, principles, trials, and design -- Volume 2. Planning, analysis, and inferential methods.</tableOfContents>
  <note type="statement of responsibility">[edited by] N. Balakrishnan.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Clinical trials</topic>
    <topic>Statistical methods</topic>
  </subject>
  <subject authority="mesh">
    <topic>Clinical Trials as Topic</topic>
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  <subject authority="mesh">
    <topic>Statistics as Topic</topic>
  </subject>
  <subject>
    <topic>Clinical trials as topic</topic>
  </subject>
  <subject>
    <topic>Medicine</topic>
  </subject>
  <subject>
    <topic>Statistics as topic</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>HEALTH &amp; FITNESS</topic>
    <topic>Holism</topic>
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    <topic>Family &amp; General Practice</topic>
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    <topic>MEDICAL</topic>
    <topic>Holistic Medicine</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Osteopathy</topic>
  </subject>
  <subject authority="fast">
    <topic>Clinical trials</topic>
    <topic>Statistical methods</topic>
  </subject>
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    <titleInfo>
      <title>Methods and applications of statistics in clinical trials</title>
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      <publisher>Hoboken, New Jersey : John Wiley &amp; Sons Inc., [2014]</publisher>
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    <identifier type="local">(DLC)  2013034342</identifier>
    <identifier type="local">(OCoLC)845515938</identifier>
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      <title>Wiley series in methods and applications of statistics</title>
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  <identifier type="uri">http://onlinelibrary.wiley.com/book/10.1002/9781118596005</identifier>
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