Emmert-Streib, Frank editor. Dehmer, Matthias 1968- editor. text bibliography Electronic books. Electronic books. gw 2013 2013 First edition. monographic eng

electronic resource

1 online resource (xx, 292 pages) : illustrations (some color). This title discusses different methods for statistically analyzing and validating data created with high-throughput methods. It focuses on systems approaches, meaning that no single gene or protein forms the basis of the analysis but rather a more or less complex biological network. Part one: General overview. Control of type I error rates for oncology biomarker discovery with high-throughput platforms -- Overview of public cancer databases, resources, and visualization tools -- Part two: Bayesian methods. Discovery of expression signatures in chronic myeloid leukemia by Bayesian model averaging -- Bayesian ranking and selection methods in microarray studies -- Multiclass classification via Bayesian variable selection with gene expression data -- Semisupervised methods for analyzing high-dimensional genomic data -- Part three: Network-based approaches -- Colorectal cancer and its molecular subsystems: construction, interpretation, and validation -- Network medicine: disease genes in molecular networks -- Inference of gene regulatory networks in breast and ovarian cancer by integrating different genomic data -- Network-module-based approaches in cancer data analysis -- Discriminant and network analysis to study origin of cancer -- Intervention and control of gene regulatory networks: theoretical framework and application to human melanoma gene regulation -- Part four: Phenotype influence of DNA copy number aberrations. Identification of recurrent DNA copy number aberrations in tumors -- The cancer cell, its entropy, and high-dimensional molecular data. edited by Frank Emmert-Streib and Matthias Dehmer. Edition statement from running title area. Includes bibliographical references and index. Cancer Diagnosis Neoplasms genetics Statistics as Topic methods Cancer Diagnosis RC270 .S73 2013eb 616.99/4075 QZ 241 Weinheim, germany : Wiley-Blackwell, [2013] (OCoLC)840878109 9783527665471 3527665471 9783527665440 3527665447 9783527665457 3527665455 9781299158511 129915851X 9783527665464 3527665463 447101 MIL http://onlinelibrary.wiley.com/book/10.1002/9783527665471 http://onlinelibrary.wiley.com/book/10.1002/9783527665471 E7B 130225 20171107083441.0 ocn834600291 eng