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  <titleInfo>
    <title>High-Density Lipoproteins : Structure, Metabolism, Function, and Therapeutics</title>
  </titleInfo>
  <name type="personal">
    <namePart>Kontush, Anatol.</namePart>
  </name>
  <name type="personal">
    <namePart>Chapman, M. John</namePart>
    <namePart type="date">1945-</namePart>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <genre authority="">Electronic books.</genre>
  <genre authority="">Llibres electrònics.</genre>
  <genre authority="local">Electronic books.</genre>
  <originInfo>
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      <placeTerm type="code" authority="marccountry">nju</placeTerm>
    </place>
    <place>
      <placeTerm type="text">Hoboken, N.J</placeTerm>
    </place>
    <publisher>John Wiley &amp; Sons, Inc.</publisher>
    <dateIssued>©2012</dateIssued>
    <dateIssued encoding="marc">2012</dateIssued>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
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    <extent>1 online resource (xxxvi, 605 pages) : illustrations (some color)</extent>
  </physicalDescription>
  <abstract>A complete guide to the role of high-density lipoproteins (HDL) in new and emerging therapies With high-density lipoproteins (HDL) playing an increasing role in cardiovascular disease prevention, there is a growing need for an in-depth look at HDL and its clinical value. This book summarizes the current state of knowledge in the field, providing for the first time a comprehensive, systematic, stylistically coherent, and up-to-date review of the composition, structure, heterogeneity, metabolism, epidemiology, genetics, and function of HDL. Divided into three main parts, High-Density Lipoproteins first examines normal HDL particles, then describes defective HDL, and finally addresses the therapeutic normalization of subnormal levels and defective biological activities of this lipoprotein class. The book highlights the functional properties of HDL, which are relevant to the pathophysiology of atherosclerosis and thrombosis, and discusses the compositional and metabolic heterogeneity of HDL particles. Readers will come away with a clear understanding of the role of HDL in biological processes, the potential value of functional HDL as a therapeutic target, and how current and emerging therapies are poised to influence the treatment of heart disease in the future.</abstract>
  <tableOfContents>Normal functional HDL -- Functionally defective HDL -- Therapeutic normalisation of subnormal levels and defective biological activities of HDL.</tableOfContents>
  <note type="statement of responsibility">edited by Anatol Kontush, M. John Chapman ; illustrations by Alexander Marienko.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>High density lipoproteins</topic>
    <topic>Metabolism</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Cardiovascular system</topic>
    <topic>Diseases</topic>
    <topic>Treatment</topic>
  </subject>
  <subject authority="mesh">
    <topic>Lipoproteins, HDL</topic>
    <topic>metabolism</topic>
  </subject>
  <subject authority="mesh">
    <topic>Arteriosclerosis</topic>
    <topic>physiopathology</topic>
  </subject>
  <subject authority="mesh">
    <topic>Cardiovascular Diseases</topic>
    <topic>therapy</topic>
  </subject>
  <subject>
    <topic>Lipoproteïnes de densitat alta</topic>
    <topic>Metabolisme</topic>
  </subject>
  <subject>
    <topic>Sistema cardiovascular</topic>
    <topic>Malalties</topic>
    <topic>Tractament</topic>
  </subject>
  <subject>
    <topic>Lipoproteïnes</topic>
    <topic>Metabolisme</topic>
  </subject>
  <subject>
    <topic>Aterosclerosi</topic>
  </subject>
  <subject>
    <topic>Sistema cardiovascular</topic>
    <topic>Malalties</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>SCIENCE</topic>
    <topic>Life Sciences</topic>
    <topic>Biochemistry</topic>
  </subject>
  <subject authority="fast">
    <topic>Cardiovascular system</topic>
    <topic>Diseases</topic>
    <topic>Treatment</topic>
  </subject>
  <subject authority="fast">
    <topic>High density lipoproteins</topic>
    <topic>Metabolism</topic>
  </subject>
  <classification authority="lcc">QP552.L5 .H55 2012eb</classification>
  <classification authority="ddc" edition="23">572/.68</classification>
  <classification authority="nlm">2012 B-375</classification>
  <classification authority="nlm">QU 85</classification>
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    <titleInfo>
      <title>High-density lipoproteins</title>
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    <originInfo>
      <publisher>Hoboken, N.J. : John Wiley &amp; Sons, Inc., ©2012</publisher>
    </originInfo>
    <identifier type="local">(DLC)  2011026194</identifier>
    <identifier type="local">(OCoLC)743275863</identifier>
  </relatedItem>
  <identifier type="isbn">9781118158647</identifier>
  <identifier type="isbn">1118158644</identifier>
  <identifier type="isbn">9781118158678</identifier>
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  <identifier type="isbn">9786613401106</identifier>
  <identifier type="isbn">6613401102</identifier>
  <identifier type="isbn">128340110X</identifier>
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  <identifier type="isbn">1118158660</identifier>
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  <identifier type="issue number">EB00062798 Recorded Books</identifier>
  <identifier type="stock number">340110 MIL</identifier>
  <identifier type="uri">http://onlinelibrary.wiley.com/book/10.1002/9781118158678</identifier>
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    <recordCreationDate encoding="marc">130304</recordCreationDate>
    <recordChangeDate encoding="iso8601">20171107091009.0</recordChangeDate>
    <recordIdentifier source="OCoLC">ocn828868898</recordIdentifier>
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