05216cam a2200757Ka 4500 ocn809920135 OCoLC 20171113140926.0 m o d cr cn||||||||| 120914s2012 gw fob 001 0 eng d 9783527630905 (electronic bk.) 3527630902 (electronic bk.) 9783527329038 (Cloth) 352732903X (Cloth) 9783527630912 (ePDF) 3527630910 (ePDF) 9783527646326 (ePub) 3527646329 (ePub) 9783527646333 (mobi) 3527646337 (mobi) 9781280665653 (MyiLibrary) 1280665653 (MyiLibrary) 9786613642585 DEBBG BV041048631 DKDLA 820120-katalog:000600786 NZ1 15121289 (OCoLC)809920135 (OCoLC)794620384 (OCoLC)823842515 10.1002/9783527630905 Wiley InterScience http://www3.interscience.wiley.com DG1 eng pn DG1 OCLCO CDX OKU OCLCQ OCLCF OCLCA UV0 COO DKDLA DEBBG YDXCP OCLCO OCLCQ OCLCO OCLCQ MAIN RA1211 QV 600 HEA eflch 615.9 23 Metabolism of drugs and other xenobiotics / edited by Pavel Anzenbacher, Ulrich M. Zanger. [electronic resource] Weinheim : Wiley-VCH, 2012. 1 online resource (734 pages) text txt rdacontent computer c rdamedia online resource cr rdacarrier Includes bibliographical references and index. Front Matter -- Biochemistry and Molecular Genetics of Drug Metabolism. Drug-Metabolizing Enzymes₆An Overview / Pavel Anzenbacher, Eva Anzenbacherov̀ -- Cytochromes P450 / F Peter Guengerich -- UDP-Glucuronosyltransferases / Christian P Strassburg, Sandra Kalthoff -- Sulfotransferases / Michael W H Coughtrie -- Glutathione -Transferases / Miroslav Dostalek, Anna-Katarina Stark -- Hydrolytic Enzymes / Bingfang Yan -- Transporting Systems / Anne T Nies, Claudia Resch, Tadashi Namisaki -- Transcriptional Regulation of Human Drug-Metabolizing Cytochrome P450 Enzymes / Zdenek Dvorak -- Importance of Pharmacogenomics / Ulrich M Zanger, Kathrin Klein, Jessica Rieger -- Metabolism of Drugs. Introduction to Drug Metabolism / Ulrich M Zanger -- Central Nervous System Drugs / Pierre Baumann, Christoph Hiemke -- Cardiovascular Drugs / Stephan Riedmaier, Ulrich M Zanger -- Anticancer Drugs / Matthias Schwab, Elke Schaeffeler, Hiltrud Brauch -- Antimicrobial Agents / Chantal Csajka, Oscar Marchetti, Oriol Manuel, Laurent Decosterd, Amalio Telenti -- Drugs against Acute and Chronic Pain / Andrew A Somogyi, Janet K Coller -- Drugs of Abuse (Including Designer Drugs) / Markus R Meyer, Hans H Maurer -- Nicotine Metabolism and its Implications / Andy Z X Zhu, Rachel F Tyndale -- Metabolism of Alcohol and its Consequences / Helmut K Seitz, Sebastian Mueller -- Metabolism of Natural Compounds. Introduction and Overview / Michael Murray -- Flavonoids / Petr Hodek -- St John's Wort (L.) / Miroslav Dostalek, Anna-Katarina Stark -- Food Components and Supplements / Alexandr Parlesak -- Metabolism of Unnatural Xenobiotics. Environmental Pollutants / Marie Stiborova -- Environmental Estrogens / Miroslav Machala, Jan Vondr̀cek -- Biotransformation of Insecticides / Corie A Ellison, Alice L Crane, James R Olson -- Index. A practice-oriented desktop reference for toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part briefly reviews the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the three main classes of xenobiotics: drugs, natural products, environmental pollutants. Selected, well-documented case studies from the most important xenobiotics classes illustrate general principles of metabolism, making this. Print version record. Xenobiotics Metabolism. Biotransformation (Metabolism) Toxicology. Biotransformation physiology. Xenobiotics metabolism. Biological Agents metabolism. Environmental Pollutants metabolism. Pharmaceutical Preparations metabolism. Pharmacokinetics. Toxicology. Biotransformation (Metabolism) fast (OCoLC)fst00832858 Toxicology. fast (OCoLC)fst01153364 Xenobiotics Metabolism. fast (OCoLC)fst01181975 Electronic books. Anzenbacher, Pavel. Zanger, Ulrich M., 1955- Wiley InterScience (Online service) Print version: Metabolism of drugs and other xenobiotics. Weinheim : Wiley-VCH, 2012 9783527329038 (OCoLC)794620384 http://onlinelibrary.wiley.com/book/10.1002/9783527630905 Wiley Online Library ddc BK 206164 206164