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  <titleInfo>
    <title>Genome organization and function in the cell nucleus</title>
  </titleInfo>
  <name type="personal">
    <namePart>Rippe, Karsten.</namePart>
  </name>
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  <genre authority="">Electronic books.</genre>
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    <place>
      <placeTerm type="text">Heidelberg, Germany</placeTerm>
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    <publisher>Wiley-VCH</publisher>
    <dateIssued>©2012</dateIssued>
    <dateIssued encoding="marc">2012</dateIssued>
    <issuance>monographic</issuance>
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  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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    <extent>1 online resource (xxv, 568 pages) : illustrations</extent>
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  <abstract>By way of its clear and logical structure, as well as abundant highresolution illustrations, this is a systematic survey of the players and pathways that control genome function in the mammalian cell nucleus. As such, this handbook and reference ties together recently gainedknowledge from a variety of scientific disciplines and approaches, dissecting all major genomic events: transcription, replication, repair, recombination and chromosome segregation. A special emphasis is put on transcriptional control, including genome-wide interactions andnon-coding RNAs, chromatin structure, ep.</abstract>
  <tableOfContents>Front Matter -- Deciphering DNA Sequence Information / Mark Kaganovich, Michael Snyder -- DNA Methylation / Carina Frauer, Fabio Spada, Heinrich Leonhardt -- Nucleosomes as Control Elements for Accessing the Genome / Mekonnen Lemma Dechassa, Karolin Luger -- Histone Modifications and Their Role as Epigenetic Marks / Karl Nightingale -- Chromatin Remodeling and Nucleosome Positioning / Gernot L̃ngst, Vladimir B Teif, Karsten Rippe -- The Folding of the Nucleosome Chain / Karsten Rippe -- The Crowded Environment of the Genome / Ron Hancock -- The Nuclear Lamina as a Chromatin Organizer / Nikolaj Zuleger, Eric C Schirmer -- Three-Dimensional Architecture of Genomes / Job Dekker -- Transcriptional Initiation: Frequency, Bursting, and Transcription Factories / Kieran Finan, Peter R Cook -- Processing of mRNA and Quality Control / Ute Schmidt, Edouard Bertrand -- The Nucleolus / Saskia Hutten, Belinda J Westman, Fraṅois-Michel Boisvert, Silvana van Koningsbruggen, Angus I Lamond -- Non-Coding RNAs as Regulators of Transcription and Genome Organization / Katalin Fejes T̤th, Gregory Hannon -- RNA Networks as Digital Control Circuits of Nuclear Functions / John S Mattick -- DNA Replication and Inheritance of Epigenetic States / Armelle Corpet, Genevïve Almouzni -- Interplay and Quality Control of DNA Damage Repair Mechanisms / Berina Eppink, Jeroen Essers, Roland Kanaar -- Higher Order Chromatin Organization and Dynamics / Hilmar Strickfaden, Thomas Cremer, Karsten Rippe -- The Mitotic Chromosome: Structure and Mechanics / John F Marko -- Meiotic Chromosome Dynamics / Nancy Kleckner, Liangran Zhang, Beth Weiner, Denise Zickler -- Understanding Genome Function: Quantitative Modeling of Chromatin Folding and Chromatin-Associated Processes / Mariliis Tark-Dame, Martijn S Luijsterburg, Dieter W Heermann, Roel van Driel -- Index.</tableOfContents>
  <note type="statement of responsibility">edited by Karsten Rippe.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Mammals</topic>
    <topic>Genetics</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Genomes</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Molecular genetics</topic>
  </subject>
  <subject>
    <topic>Genomes</topic>
  </subject>
  <subject>
    <topic>Mammals</topic>
    <topic>Genetics</topic>
  </subject>
  <subject>
    <topic>Molecular genetics</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>SCIENCE</topic>
    <topic>Life Sciences</topic>
    <topic>Genetics &amp; Genomics</topic>
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  <subject authority="fast">
    <topic>Genomes</topic>
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  <subject authority="fast">
    <topic>Mammals</topic>
    <topic>Genetics</topic>
  </subject>
  <subject authority="fast">
    <topic>Molecular genetics</topic>
  </subject>
  <classification authority="lcc">QH447 .G463 2012eb</classification>
  <classification authority="ddc" edition="23">572.8619</classification>
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      <title>Genome organization and function in the cell nucleus</title>
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      <publisher>Weinheim : Wiley-VCH ; Chichester : John Wiley [distributor], 2011</publisher>
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    <identifier type="local">(OCoLC)751739775</identifier>
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  <identifier type="isbn">9783527640010</identifier>
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  <identifier type="stock number">10.1002/9783527639991 Wiley InterScience</identifier>
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    <recordCreationDate encoding="marc">110806</recordCreationDate>
    <recordChangeDate encoding="iso8601">20171114083122.0</recordChangeDate>
    <recordIdentifier source="OCoLC">ocn808347872</recordIdentifier>
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