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  <titleInfo>
    <title>Lead optimization for medicinal chemists : pharmacokinetic properties of functional groups and organic compounds</title>
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  <name type="personal">
    <namePart>Dörwald, Florencio Zaragoza.</namePart>
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  <genre authority="">Electronic books.</genre>
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    <dateIssued encoding="marc">2012</dateIssued>
    <copyrightDate encoding="marc">2012</copyrightDate>
    <issuance>monographic</issuance>
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    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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    <extent>1 online resource (xvi, 605 pages) : illustrations</extent>
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  <abstract>Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and sy.</abstract>
  <tableOfContents>pt. 1. Introduction -- pt. 2. The pharmacokinetic properties of compound classes.</tableOfContents>
  <note type="statement of responsibility">Florencioa Zaragoza Dörwald.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Pharmaceutical chemistry</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Drug Guides</topic>
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  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Nursing</topic>
    <topic>Pharmacology</topic>
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  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Pharmacology</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Pharmacy</topic>
  </subject>
  <subject authority="fast">
    <topic>Pharmaceutical chemistry</topic>
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  <classification authority="lcc">RS403</classification>
  <classification authority="ddc">615.19</classification>
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      <title>Lead optimization for medicinal chemists</title>
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      <namePart>Dörwald, Florencio Zaragoza.</namePart>
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      <publisher>Weinheim : Wiley-VCH, ©2012</publisher>
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    <identifier type="local">(OCoLC)793414338</identifier>
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  <identifier type="isbn">9783527645640</identifier>
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  <identifier type="uri">http://onlinelibrary.wiley.com/book/10.1002/9783527645640</identifier>
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