03331cam a2200733Ii 4500 ocn805654697 OCoLC 20171114084244.0 m o d cr ||||||||||| 120809t20122012gw a ob 001 0 eng d 9783527645640 3527645640 9783527645664 3527645667 9783527332267 352733226X 9783527645657 3527645659 9783527645671 3527645675 9781283893244 128389324X AU@ 000050590692 AU@ 000053019049 NZ1 14976578 NLGGC 356818578 DKDLA 820120-katalog:000599880 GBVCP 790199491 DEBBG BV043394967 (OCoLC)805654697 (OCoLC)961515877 (OCoLC)962633579 (OCoLC)966211547 YDXCP eng rda pn YDXCP E7B OCLCQ COO OCLCO DG1 EBLCP N$T MHW CCO IDEBK OCLCF IUL OCLCQ D6H AZK LOA MAIN RS403 MED 023000 bisacsh MED 058170 bisacsh MED 071000 bisacsh MED 072000 bisacsh 615.19 Dörwald, Florencio Zaragoza. Lead optimization for medicinal chemists : pharmacokinetic properties of functional groups and organic compounds / Florencioa Zaragoza Dörwald. [electronic resource] Weinheim : Wiley-VCH Verlag GmBH & Co., [2012] ©2012 1 online resource (xvi, 605 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier Bibliography Includes bibliographical references and index. pt. 1. Introduction -- pt. 2. The pharmacokinetic properties of compound classes. Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and sy. Online resource; title from home page (viewed May 23, 2014). Pharmaceutical chemistry. MEDICAL Drug Guides. bisacsh MEDICAL Nursing Pharmacology. bisacsh MEDICAL Pharmacology. bisacsh MEDICAL Pharmacy. bisacsh Pharmaceutical chemistry. fast (OCoLC)fst01060115 Electronic books. Electronic books. local Print version: Dörwald, Florencio Zaragoza. Lead optimization for medicinal chemists. Weinheim : Wiley-VCH, ©2012 9783527332267 (OCoLC)793414338 http://onlinelibrary.wiley.com/book/10.1002/9783527645640 Wiley Online Library ddc BK 206101 206101