<?xml version="1.0" encoding="UTF-8"?>
<mods xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://www.loc.gov/mods/v3" version="3.1" xsi:schemaLocation="http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-1.xsd">
  <titleInfo>
    <title>Applications of transition metal catalysis in drug discovery and development : an industrial perspective</title>
  </titleInfo>
  <name type="personal">
    <namePart>Crawley, Matthew L.</namePart>
  </name>
  <name type="personal">
    <namePart>Trost, Barry M.</namePart>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <genre authority="">Electronic books.</genre>
  <genre authority="local">Electronic books.</genre>
  <originInfo>
    <place>
      <placeTerm type="code" authority="marccountry">nju</placeTerm>
    </place>
    <place>
      <placeTerm type="text">Hoboken, N.J</placeTerm>
    </place>
    <publisher>John Wiley &amp; Sons</publisher>
    <dateIssued>©2012</dateIssued>
    <dateIssued encoding="marc">2012</dateIssued>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
    <form authority="gmd">electronic resource</form>
    <extent>1 online resource (xviii, 356 pages)</extent>
  </physicalDescription>
  <abstract>"This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development."--Provided by publisher.</abstract>
  <tableOfContents>Applications of TRANSITION METAL CATALYSIS in Drug Discovery and Development; Contents; Preface; Contributors; About the Authors; 1 Transition Metal Catalysis in the Pharmaceutical Industry; 1.1 Overview of Catalysis; 1.2 Transition Metal Catalysis in the Pharmaceutical Industry; 1.2.1 Cross-Couplings for the Formation of Carbon-Carbon Bonds; 1.2.2 Cross-Couplings for the Formation of Carbon-Heteroatom Bonds; 1.2.3 Asymmetric Hydrogenation; 1.2.4 Oxidative Catalysis; 1.2.5 Asymmetric Addition Reactions; 1.2.6 Metathesis; 1.3 Challenges in Taking Catalysis to Industrial Scales.</tableOfContents>
  <note type="statement of responsibility">edited by Matthew L. Crawley, Barry M. Trost.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Catalysis</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Transition metals</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Pharmacy</topic>
  </subject>
  <subject authority="mesh">
    <topic>Drug Discovery</topic>
  </subject>
  <subject authority="mesh">
    <topic>Catalysis</topic>
  </subject>
  <subject authority="mesh">
    <topic>Pharmaceutical Preparations</topic>
    <topic>chemistry</topic>
  </subject>
  <subject authority="mesh">
    <topic>Transition Elements</topic>
  </subject>
  <subject>
    <topic>Medicine</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Drug Guides</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Nursing</topic>
    <topic>Pharmacology</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Pharmacology</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Pharmacy</topic>
  </subject>
  <subject authority="fast">
    <topic>Catalysis</topic>
  </subject>
  <subject authority="fast">
    <topic>Pharmacy</topic>
  </subject>
  <subject authority="fast">
    <topic>Transition metals</topic>
  </subject>
  <classification authority="lcc">QV744</classification>
  <classification authority="ddc" edition="23">615.1/9</classification>
  <classification authority="nlm">QV 744</classification>
  <relatedItem type="otherFormat" displayLabel="Print version:">
    <titleInfo>
      <title>Applications of Transition Metal Catalysis in Drug Discovery and Development : An Industrial Perspective</title>
    </titleInfo>
    <name>
      <namePart>Crawley, Matthew L.</namePart>
    </name>
    <originInfo>
      <publisher>Hoboken : John Wiley &amp; Sons, ©2012</publisher>
    </originInfo>
  </relatedItem>
  <identifier type="isbn">9781118309872</identifier>
  <identifier type="isbn">1118309871</identifier>
  <identifier type="isbn">9781118309865</identifier>
  <identifier type="isbn">1118309863</identifier>
  <identifier type="isbn">9780470631324</identifier>
  <identifier type="isbn">0470631325</identifier>
  <identifier type="isbn">9781280592386</identifier>
  <identifier type="isbn">1280592389</identifier>
  <identifier type="isbn">9781118309834</identifier>
  <identifier type="isbn">1118309839</identifier>
  <identifier type="lccn" invalid="yes"/>
  <identifier type="issue number">EB00063317 Recorded Books</identifier>
  <identifier type="stock number">362221 MIL</identifier>
  <identifier type="uri">http://onlinelibrary.wiley.com/book/10.1002/9781118309872</identifier>
  <location>
    <url>http://onlinelibrary.wiley.com/book/10.1002/9781118309872</url>
  </location>
  <recordInfo>
    <recordContentSource authority="marcorg">EBLCP</recordContentSource>
    <recordCreationDate encoding="marc">120521</recordCreationDate>
    <recordChangeDate encoding="iso8601">20171114094555.0</recordChangeDate>
    <recordIdentifier source="OCoLC">ocn793995928</recordIdentifier>
    <languageOfCataloging>
      <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
    </languageOfCataloging>
  </recordInfo>
</mods>
