04502cam a2200865Ia 4500 ocn793995928 OCoLC 20171114094555.0 m o d cr |n|---||||| 120521s2012 nju ob 001 0 eng d 2011047552 9781118309872 (electronic bk.) 1118309871 (electronic bk.) 9781118309865 (electronic bk.) 1118309863 (electronic bk.) 9780470631324 (hbk.) 0470631325 (hbk.) 9781280592386 (MyiLibrary) 1280592389 (MyiLibrary) 9781118309834 (electronic bk.) 1118309839 (electronic bk.) 9786613622211 EB00063317 Recorded Books AU@ 000049595600 DEBBG BV042795908 DKDLA 820120-katalog:000600473 NZ1 14976958 DEBBG BV043394553 (OCoLC)793995928 (OCoLC)805829733 (OCoLC)860514930 (OCoLC)898985523 (OCoLC)961497879 (OCoLC)962650616 (OCoLC)966234100 362221 MIL EBLCP eng pn EBLCP OCLCQ N$T MERUC UIU DG1 MYG YDXCP CDX OCLCO OCLCQ OCLCO OCLCQ COO E7B OCLCF OCLCQ RECBK OCLCQ AZK LOA OCLCO OCLCA MAIN QV744 QV 744 MED 023000 bisacsh MED 058170 bisacsh MED 071000 bisacsh MED 072000 bisacsh 615.1/9 23 Applications of transition metal catalysis in drug discovery and development : an industrial perspective / edited by Matthew L. Crawley, Barry M. Trost. [electronic resource] Hoboken, N.J. : John Wiley & Sons, ©2012. 1 online resource (xviii, 356 pages) text txt rdacontent computer c rdamedia online resource cr rdacarrier data file rda Bibliography Includes bibliographical references and index. Applications of TRANSITION METAL CATALYSIS in Drug Discovery and Development; Contents; Preface; Contributors; About the Authors; 1 Transition Metal Catalysis in the Pharmaceutical Industry; 1.1 Overview of Catalysis; 1.2 Transition Metal Catalysis in the Pharmaceutical Industry; 1.2.1 Cross-Couplings for the Formation of Carbon-Carbon Bonds; 1.2.2 Cross-Couplings for the Formation of Carbon-Heteroatom Bonds; 1.2.3 Asymmetric Hydrogenation; 1.2.4 Oxidative Catalysis; 1.2.5 Asymmetric Addition Reactions; 1.2.6 Metathesis; 1.3 Challenges in Taking Catalysis to Industrial Scales. "This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development."--Provided by publisher. Print version record. Catalysis. Transition metals. Pharmacy. Drug Discovery. Catalysis. Pharmaceutical Preparations chemistry. Transition Elements. Medicine. MEDICAL Drug Guides. bisacsh MEDICAL Nursing Pharmacology. bisacsh MEDICAL Pharmacology. bisacsh MEDICAL Pharmacy. bisacsh Catalysis. fast (OCoLC)fst00848867 Pharmacy. fast (OCoLC)fst01060285 Transition metals. fast (OCoLC)fst01154781 Electronic books. Electronic books. local Crawley, Matthew L. Trost, Barry M. Print version: Crawley, Matthew L. Applications of Transition Metal Catalysis in Drug Discovery and Development : An Industrial Perspective. Hoboken : John Wiley & Sons, ©2012 9780470631324 http://onlinelibrary.wiley.com/book/10.1002/9781118309872 Wiley Online Library ddc BK 205913 205913