04626cam a2200793Ia 4500 ocn793995927 OCoLC 20171114095033.0 m o d cr cn|---||||| 120521s2012 njua ob 001 0 eng d 2011047556 9781118268667 (electronic bk.) 1118268660 (electronic bk.) 9781118268506 (electronic bk.) 1118268504 (electronic bk.) 9781280768736 (MyiLibrary) 1280768738 (MyiLibrary) 9781118267516 (electronic bk.) 1118267516 (electronic bk.) 9780470592045 (Cloth) 0470592044 (Cloth) 9786613679505 EB00066660 Recorded Books AU@ 000049595548 DEBBG BV041056690 DEBBG BV041828933 DEBSZ 431077274 DKDLA 820120-katalog:000599850 NZ1 14976563 (OCoLC)793995927 (OCoLC)795632063 (OCoLC)865012221 (OCoLC)961535317 (OCoLC)962593254 (OCoLC)966197830 367950 MIL EBLCP eng pn EBLCP OCLCQ N$T MERUC UIU DG1 CDX TXA YDXCP OCLCA E7B OCLCQ COO DEBBG OCLCQ RECBK OCLCF DEBSZ OCLCQ D6H AZK LOA OCLCO OCLCA MAIN QP606 .T44 T45 2012 QU 56 SCI 049000 bisacsh SCI 029000 bisacsh 572.7 572.8 572.86 Telomerases : chemistry, biology and clinical applications / edited by Neal F. Lue and Chantal Autexier. [electronic resource] Hoboken : John Wiley & Sons, 2012. 1 online resource (x, [16], 308 pages) : illustrations (some color) text txt rdacontent computer c rdamedia online resource cr rdacarrier data file rda Bibliography Includes bibliographical references and index. The telomerase complex : an overview / Johanna Mancini and Chantal Autexier -- Telomerase RNA : structure, function, and molecular mechanisms / Yehudi Tzfati and Julian J.-L. Chen -- TERT structure, function, and molecular mechanisms / Emmanuel Skordalakes and Neal F. Lue -- Telomerase biogenesis : RNA Processing, trafficking and protein Interactions / Tara Beattie and Pascal Chartrand -- Transcriptional regulation of human telomerase / Antonella Farsetti and Yu-Sheng Cong -- Telomerase regulation and telomere length homeostasis / Joachim Lingner and David Shore -- Telomere structure in telomerase regulation / Momchil D. Vodenicharov and Raymund J. Wellinger -- Off-telomere functions of telomerase / Kenkichi Masutomi and William C. Hahn -- Murine Models of Dysfunctional Telomeres and Telomerase / Yie Liu and Lea Harrington -- Cellular senescence, telomerase, and cancer in human cells / Phillip G. Smiraldo [and others] -- Telomerase, retrotransposons, and evolution / Irina R. Arkhipova. "This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research. Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase. Other topics include telomerase biogenesis, transcriptional and post-translational regulation, off-telomere functions of telomerase and the role of telomerase in cellular senescence, aging and cancer. Its relationship to retrotransposons, a class of mobile genetic elements that shares similarities with telomerase and serves as telomeres in selected organisms, are also reviewed"--Provided by publisher. Print version record. Telomerase Physiology. Telomerase Metabolism. Telomerase Genetics. Geriatrics. Natural history. Science. SCIENCE Life Sciences Molecular Biology. bisacsh SCIENCE Life Sciences Genetics & Genomics. bisacsh Science. fast (OCoLC)fst01108176 Telomerase. Electronic books. Electronic books. local Lue, Neal F., 1962- Autexier, Chantal, 1963- Print version: Lue, Neal. Telomerases : Chemistry, Biology and Clinical Applications. Hoboken : John Wiley & Sons, ©2012 9780470592045 http://onlinelibrary.wiley.com/book/10.1002/9781118268667 Wiley Online Library ddc BK 205912 205912