Telomerases : chemistry, biology and clinical applications / edited by Neal F. Lue and Chantal Autexier. [electronic resource] Lue, Neal F., 1962- Autexier, Chantal, 1963- Telomerase Physiology. Telomerase Metabolism. Telomerase Genetics. Geriatrics. Telomerase. QP606 .T44 T45 2012 572.7 572.8 572.86 Includes bibliographical references and index. Print version record. "This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research. Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase. Other topics include telomerase biogenesis, transcriptional and post-translational regulation, off-telomere functions of telomerase and the role of telomerase in cellular senescence, aging and cancer. Its relationship to retrotransposons, a class of mobile genetic elements that shares similarities with telomerase and serves as telomeres in selected organisms, are also reviewed"--Provided by publisher. Hoboken : John Wiley & Sons, 2012. 2012. 2012 Text 1 online resource (x, [16], 308 pages) : http://onlinelibrary.wiley.com/book/10.1002/9781118268667 eng Telomerases : Chemistry, Biology and Clinical Applications. Telomerases : Chemistry, Biology and Clinical Applications.