03877cam a2200697 a 4500 ocn792941569 OCoLC 20171114100436.0 m o d cr ||||||||||| 120430s2012 enk ob 001 0 eng 2012017805 9781118405345 (ePub) 111840534X (ePub) 9781118405352 (Adobe PDF) 1118405358 (Adobe PDF) 9781118405369 (MobiPocket) 1118405366 (MobiPocket) 9781118405338 (electronic bk.) 1118405331 (electronic bk.) 9781118390115 (pbk. ; alk. paper) AU@ 000049094256 DEBSZ 43133174X NLGGC 356816389 NZ1 15922081 ZWZ 194585972 DEBBG BV043394505 (OCoLC)792941569 (OCoLC)957521372 (OCoLC)957613858 (OCoLC)966527031 DLC eng pn DLC DG1 UIU YDXCP EBLCP N$T MHW NLGGC UKDOC DEBSZ OCLCQ OCLCO OCLCQ DEBBG OCLCA pcc MAIN QR395 .R48 2013 QW 168 SCI 008000 bisacsh SCI 045000 bisacsh 579.2/5 23 Reverse genetics of RNA viruses : applications and perspectives / [edited by] Anne Bridgen. [electronic resource] Chichester, West Sussex, UK ; Hoboken, NJ : Wiley - Blackwell, 2012. 1 online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier Includes bibliographical references and index. Definitions of reverse genetics, +ve, -ve, sense and doubled stranded (DS) RNA viruses / Anne Bridgen -- Coronavirus reverse genetics / Paul Britton -- Hepatitis C and use of reverse genetics in drug design / Natalia Frias Staheli -- Norovirus reverse genetics / Ian Goodfellow -- Rhabdovirus reverse genetics / Klaus Conzelmann -- Modification of measles virus and application to pathogenesis studies / Paul Duprex -- Bunyavirus reverse genetics and application to interaction with host cells / Richard Elliott -- Influenza A virus vaccines / Wendy Barclay -- Bluetongue virus reverse genetics / Mark Boyce -- Reovirus reverse genetics / Rob Hoeben -- Reverse genetics and quasispecies / Marco Vignuzzi -- Summary and perspectives / Anne Bridgen. Reverse genetics, the genetic manipulation of RNA viruses to create a wild-type or modified virus, has led to important advances in our understanding of viral gene function and interaction with host cells. Since many severe viral human and animal pathogens are RNA viruses, including those responsible for polio, measles, rotaviral diarrhoea and influenza infections, it is also an extremely powerful technique with important potential application for the prevention and control of a range of human and animal viral diseases. Reverse Genetics of RNA Viruses provides a comprehensive. Print version record and CIP data provided by publisher. RNA viruses Genetic aspects. Reverse genetics. RNA Viruses genetics. Reverse Genetics methods. RNA, Viral genetics. Viral Proteins genetics. Viral Vaccines. SCIENCE Life Sciences Biology. bisacsh SCIENCE Life Sciences Microbiology. bisacsh Electronic books. Bridgen, Anne, 1961- Print version: Reverse genetics of RNA viruses. Chichester, West Sussex : John Wiley & Sons, 2012 9781118390115 (DLC) 2012016778 http://onlinelibrary.wiley.com/book/10.1002/9781118405338 Wiley Online Library ddc BK 205863 205863