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  <titleInfo>
    <title>Chitosan-based systems for biopharmaceuticals : delivery, targeting, and polymer therapeutics</title>
  </titleInfo>
  <name type="personal">
    <namePart>Sarmento, Bruno.</namePart>
  </name>
  <name type="personal">
    <namePart>Neves, José das</namePart>
    <namePart type="date">1978-</namePart>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <genre authority="">Electronic books.</genre>
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    <place>
      <placeTerm type="text">Chichester, West Sussex</placeTerm>
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    <publisher>John Wiley &amp; Sons</publisher>
    <dateIssued>2012</dateIssued>
    <issuance>monographic</issuance>
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  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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    <extent>1 online resource (xxvi, 556 pages) : illustrations</extent>
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  <tableOfContents>Chemical and technological advances in chitins and chitosans useful for the formulation of biopharmaceuticals / Riccardo A.A. Muzzarelli -- Physical properties of chitosan and derivatives in sol and gel states / Marguerite Rinaudo -- Absorption promotion properties of chitosan and derivatives / Akira Yamamoto -- Biocompatibility and biodegradation of chitosan and derivatives / Ahmad Sukari Halim [and others] -- Biological and pharmacological activity of chitosan and derivatives / Teresa Cunha [and others] -- Biological, chemical, and physical compatibility of chitosan and biopharmaceuticals / Masayuki Ishihara [and others] -- Approaches for functional modification or crosslinking of chitosan / A. Anitha [and others] -- Use of chitosan and derivatives in conventional biopharmaceutical dosage forms formulation / Teófilo Vasconcelos, Pedro Barrocas, Rui Cerdeira -- Manufacture techniques of chitosan-based microparticles and nanoparticles for biopharmaceuticals / Franca Ferrari [and others] -- Chitosan and derivatives for biopharmaceutical use : mucoadhesive properties / Katharina Leithner, Andreas Bernkop-Schnürch -- Chitosan-based systems for mucosal delivery of biopharmaceuticals / Sonia Al-Qadi, Ana Grenha, Carmen Remuñán-López -- Chitosan-based delivery systems for mucosal vaccination / Gerrit Borchard, Farnaz Esmaeili, Simon Heuking -- Chitosan-based nanoparticulates for oral delivery of biopharmaceuticals / Filipa Antunes, Fernanda Andrade, Bruno Sarmento.</tableOfContents>
  <tableOfContents>Chitosan-based systems for ocular delivery of biopharmaceuticals / Suresh P. Vyas, Rishi Paliwal, Shivani Rai Paliwal -- Chemical modification of chitosan for delivery of DNA and SIRNA / You-Kyoung Kim [and others] -- Target-specific chitosan-based nanoparticle systems for nucleic acid delivery / Shardool Jain, Mansoor Amiji -- Functional PEGylated chitosan systems for biopharmaceuticals / Hee-Jeong Cho [and others] -- Stimuli-sensitive chitosan-based systems for biopharmaceuticals / Cuiping Zhai, Jinfang Yuan, Qingyu Gao -- Chitosan copolymers for biopharmaceuticals / Ramon Novoa-Carballal, Ricardo Riguera, Eduardo Fernandez-Megia -- Application of chitosan for anti-cancer biopharmaceutical delivery / Claudia Philippi [and others] -- Chitosan-based biopharmaceuticals scaffolds in tissue engineering and regenerative medicine / Tao Jiang [and others] -- Wound healing properties of chitosan and its use in wound dressing biopharmaceuticals / Tyler G. St. Denis [and others] -- Toxicological properties of chitosan and derivatives for biopharmaceutical applications / Thomas J. Kean, Maya Thanou -- Regulatory status of chitosan and derivatives / Michael Dornish, David S. Kaplan, Sambasiva R. Arepalli -- Patentability and intellectual property issues related with chitosan-based biopharmaceutical products / Mafalda Videira, Rogrio Gaspar -- Quality control and good manufacturing practice (GMP) for chitosan-based biopharmaceutical products / Torsten Richter, Maika Gulich, Katja Richter -- Preclinical and clinical use of chitosan and derivatives for biopharmaceuticals : from preclinical research to the bedside / David A. Zaharoff [and others].</tableOfContents>
  <note type="statement of responsibility">edited by Bruno Sarmento, José das Neves.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Chitosan</topic>
    <topic>Therapeutic use</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Polymers in medicine</topic>
  </subject>
  <subject authority="mesh">
    <topic>Biopharmaceutics</topic>
  </subject>
  <subject authority="mesh">
    <topic>Chitosan</topic>
    <topic>therapeutic use</topic>
  </subject>
  <subject authority="mesh">
    <topic>Biopolymers</topic>
    <topic>therapeutic use</topic>
  </subject>
  <subject authority="mesh">
    <topic>Drug Carriers</topic>
    <topic>therapeutic use</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Drug Guides</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Nursing</topic>
    <topic>Pharmacology</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Pharmacology</topic>
  </subject>
  <subject authority="bisacsh">
    <topic>MEDICAL</topic>
    <topic>Pharmacy</topic>
  </subject>
  <subject authority="fast">
    <topic>Chitosan</topic>
    <topic>Therapeutic use</topic>
  </subject>
  <subject authority="fast">
    <topic>Polymers in medicine</topic>
  </subject>
  <classification authority="lcc">RM666.C39 C45 2012eb</classification>
  <classification authority="ddc" edition="23">615.1/9</classification>
  <classification authority="nlm">QU 83</classification>
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  <identifier type="stock number">10.1002/9781119962977 Wiley InterScience</identifier>
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